[HTML][HTML] Regulation of autophagy fires up the cold tumor microenvironment to improve cancer immunotherapy

Z Jin, X Sun, Y Wang, C Zhou, H Yang… - Frontiers in …, 2022 - frontiersin.org
Immunotherapies, such as immune checkpoint inhibitors (ICIs) and chimeric antigen
receptor (CAR) T cells, have revolutionized the treatment of patients with advanced and …

[HTML][HTML] Advances of targeted therapy for hepatocellular carcinoma

M Niu, M Yi, N Li, K Wu, K Wu - Frontiers in Oncology, 2021 - frontiersin.org
Hepatocellular carcinoma (HCC) is one of the common and fatal malignancies, which is a
significant global health problem. The clinical applicability of traditional surgery and other …

[HTML][HTML] The efficacy of tumor mutation burden as a biomarker of response to immune checkpoint inhibitors

C Moeckel, K Bakhl, I Georgakopoulos-Soares… - International journal of …, 2023 - mdpi.com
Cancer is one of the leading causes of death in the world; therefore, extensive research has
been dedicated to exploring potential therapeutics, including immune checkpoint inhibitors …

[HTML][HTML] Tumor vasculature vs tumor cell targeting: Understanding the latest trends in using functional nanoparticles for cancer treatment

NS Awad, NM Salkho, WH Abuwatfa, V Paul… - OpenNano, 2023 - Elsevier
Delivering drugs to tumors using nanoparticles (NPs) has shown promising potential in
promoting targeted drug delivery of antineoplastic agents to enhance their efficiency while …

[HTML][HTML] NRP1 interacts with endoglin and VEGFR2 to modulate VEGF signaling and endothelial cell sprouting

S Sharma, M Ehrlich, M Zhang, GC Blobe… - Communications …, 2024 - nature.com
Endothelial cells express neuropilin 1 (NRP1), endoglin (ENG) and vascular endothelial
growth factor receptor 2 (VEGFR2), which regulate VEGF-A-mediated vascular development …

[HTML][HTML] Mechanosensory feedback loops during chronic inflammation

S Saha, D Müller, AG Clark - Frontiers in Cell and Developmental …, 2023 - frontiersin.org
Epithelial tissues are crucial to maintaining healthy organization and compartmentalization
in various organs and act as a first line of defense against infection in barrier organs such as …

[HTML][HTML] Diagnostic, prognostic, and therapeutic role for angiogenesis markers in head and neck squamous cell carcinoma: a narrative review

L Alessandrini, L Astolfi, A Daloiso, M Sbaraglia… - International Journal of …, 2023 - mdpi.com
Despite refinements to diagnostic and therapeutic approaches over the last two decades,
the outcome of patients with head and neck squamous cell carcinoma (HNSCC) has not …

CD105: tumor diagnosis, prognostic marker and future tumor therapeutic target

L Li, L Zhong, C Tang, L Gan, T Mo, J Na, J He… - Clinical and …, 2022 - Springer
Cancer is one of the diseases with the highest morbidity and mortality rates worldwide, and
its therapeutic options are inadequate. The endothelial glycoprotein, also known as CD105 …

[HTML][HTML] An overview of angiogenesis in bladder cancer

G Elayat, I Punev, A Selim - Current Oncology Reports, 2023 - Springer
Abstract Purpose of the Review Angiogenesis plays a key role in bladder cancer (BC)
pathogenesis. In the last two decades, an increasing number of publications depicting a …

[HTML][HTML] The Role of Specialized Pro-Resolving Lipid Mediators in Inflammation-Induced Carcinogenesis

W Torres, JL Pérez, MP Díaz, L D'Marco… - International Journal of …, 2023 - mdpi.com
Cancer is a process involving cell mutation, increased proliferation, invasion, and
metastasis. Over the years, this condition has represented one of the most concerning health …