Extracellular vesicles (EVs) are a means of cell-to-cell communication and can facilitate the
exchange of a broad array of molecules between adjacent or distant cells. Platelets are …

Nanomaterial-based drug delivery systems (NBDDS) are widely used to improve the safety
and therapeutic efficacy of encapsulated drugs due to their unique physicochemical and …

Objective: The aim of this study was to identify a mortality benefit with the use of whole blood
(WB) as part of the resuscitation of bleeding trauma patients. Background: Blood component …

There is much interest in the use of extracellular vesicles (EVs) as a subcellular therapy for
regenerative medicine and drug delivery. Blood-borne platelets represent a source of …

Every year more than 500,000 deaths are attributed to trauma worldwide and severe
hemorrhage is present in most of them. Transfused platelets have been shown to improve …

Extracellular vesicles (EVs) have attracted rising interests in the cardiovascular field not only
because they serve as serological markers for circulatory disorders but also because they …

Extracellular vesicles (EVs) present a great potential for the development of new treatments
in the biomedical field. To be used as therapeutics, many different sources have been used …

Endothelium has a rich vesicular network that allows the exchange of macromolecules
between blood and parenchymal cells. This feature of endothelial cells, along with their …

Autologous blood products, such as platelet-rich plasma (PRP), are gaining increasing
interest in different fields of regenerative medicine. Although growth factors, the main …

Extracellular vesicles (EVs) are increasingly recognised as a pivotal player in cell-cell
communication, an attribute of EVs that derives from their ability to transport bioactive …