MYC, a major oncogenic transcription factor, regulates target genes involved in various
pathways such as cell proliferation, metabolism and immune evasion, playing a critical role …

Simple Summary Over 70% of the liver comprises of parenchymal cells (named
hepatocytes) and the rest 30% of cells are the non-parenchymal cells, which include …

Alcohol consumption is a heritable behavior seriously endangers human health. However,
genetic studies on alcohol consumption primarily focuses on common variants, while …

Alcoholic liver disease (ALD) is currently considered a global healthcare problem with
limited pharmacological treatment options. There are abundant cell types in the liver, such …

While a few works have shown that Mettl3 plays oncogenic roles in hepatocellular
carcinoma (HCC), its function in early HCC tumorigenesis remains unclear. In Mettl3 …

Alcohol‐associated liver disease is a major cause of alcohol‐related mortality. However, the
mechanisms underlying disease progression are not fully understood. Recently we found …

Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disease with
multifactorial pathogenesis; histone demethylases (HDMs) are emerging as attractive …

Background & Aims Alcohol-associated liver disease (ALD) is a major cause of alcohol-
related mortality. Sex is an important variable; however, the mechanism behind sex …

Alcohol-associated liver disease (ALD) is a substantial cause of morbidity and mortality
worldwide and represents a spectrum of liver injury beginning with hepatic steatosis (fatty …

Single ethanol binge causes severe liver injury in mice fed... : Hepatology Communications
Single ethanol binge causes severe liver injury in mice fed Western diet : Hepatology …