Overview of the 2022 WHO classification of adrenal cortical tumors

O Mete, LA Erickson, CC Juhlin, RR de Krijger… - Endocrine …, 2022 - Springer
The new WHO classification of adrenal cortical proliferations reflects translational advances
in the fields of endocrine pathology, oncology and molecular biology. By adopting a …

Update in adrenocortical carcinoma

M Fassnacht, M Kroiss, B Allolio - The Journal of Clinical …, 2013 - academic.oup.com
Adrenocortical carcinoma (ACC) is an orphan malignancy that has attracted increasing
attention during the last decade. Here we provide an update on advances in the field since …

European Society of Endocrinology Clinical Practice Guidelines on the management of adrenocortical carcinoma in adults, in collaboration with the European Network …

M Fassnacht, OM Dekkers, T Else… - European journal of …, 2018 - academic.oup.com
Adrenocortical carcinoma (ACC) is a rare and in most cases steroid hormone-producing
tumor with variable prognosis. The purpose of these guidelines is to provide clinicians with …

Diagnostic, prognostic, and predictive role of Ki67 proliferative index in neuroendocrine and endocrine neoplasms: past, present, and future

S La Rosa - Endocrine Pathology, 2023 - Springer
The introduction of Ki67 immunohistochemistry in the work-up of neuroendocrine neoplasms
(NENs) has opened a new approach for their diagnosis and prognostic evaluation. Since the …

Adrenocortical carcinoma: Updates of clinical and pathological features after renewed world health organisation classification and pathology staging

AK Lam - Biomedicines, 2021 - mdpi.com
Adrenocortical carcinoma (ACC) is a heterogenous group of diseases with different clinical
behaviour between adult and paediatric patients. In addition, three histological variants …

What did we learn from the molecular biology of adrenal cortical neoplasia? From histopathology to translational genomics

CC Juhlin, J Bertherat, TJ Giordano, GD Hammer… - Endocrine …, 2021 - Springer
Approximately one-tenth of the general population exhibit adrenal cortical nodules, and the
incidence has increased. Afflicted patients display a multifaceted symptomatology …

Antineoplastic effects of 1, 25 (OH) 2D3 and its analogs in breast, prostate and colorectal cancer

C Leyssens, L Verlinden… - Endocrine-related …, 2013 - erc.bioscientifica.com
Breast cancer is the most prevalent type of cancer in women and responsible for significant
female cancer-related mortality worldwide. In the Western world, over 80% of breast cancers …

Validation of the prognostic role of the" Helsinki Score” in 225 cases of adrenocortical carcinoma

E Duregon, R Cappellesso, V Maffeis, B Zaggia… - Human Pathology, 2017 - Elsevier
Adrenocortical carcinoma patient prognosis is extremely variable and poorly predictable.
The newly introduced Helsinki Score is the first so far proposed diagnostic and prognostic …

Treatment of adrenocortical carcinoma

A Vaidya, M Nehs, K Kilbridge - Surgical Pathology Clinics, 2019 - surgpath.theclinics.com
Adrenocortical carcinoma (ACC) is a rare malignancy with a poor prognosis. ACC is capable
of secreting excess adrenocortical hormones, which can compound morbidity and …

Diagnostic and prognostic biomarkers of adrenal cortical carcinoma

O Mete, H Gucer, M Kefeli, SL Asa - The American journal of …, 2018 - journals.lww.com
The diagnosis of low-grade adrenal cortical carcinoma (ACC) confined to the adrenal gland
can be challenging. Although there are diagnostic and prognostic molecular tests for ACC …