Endothelial cells are a constitutive part of the heart and vasculature and form a crucial link
between the cardiovascular system and the immune system. Besides their commonly …

Mechanosensing describes the ability of a cell to sense mechanical cues of its
microenvironment, including not only all components of force, stress, and strain but also …

Bonds between adhesion molecules are often mechanically stressed. A striking example is
the tensile force applied to selectin–ligand bonds, which mediate the tethering and rolling of …

Rolling adhesion on vascular surfaces is the first step in recruiting circulating leukocytes,
hematopoietic progenitors, or platelets to specific organs or to sites of infection or injury …

This is the second edition of our little red book Lectins published in 1989. In the intervening
years well over 10,000 articles have appeared with lectins as the main subject, and more …

Multivalent protein–carbohydrate interactions regulate essential cellular events, including
cell proliferation, adhesion and death. These multivalent interactions can create …

Interactions of selectins with cell-surface glycoconjugates mediate tethering and rolling
adhesion of leukocytes and platelets on vascular surfaces. Recent studies have helped …

In response to hemorrhage, circulating platelets adhere to exposed subendothelial tissues
and then recruit additional platelets into aggregates that function as procoagulant surfaces …

Many small proteins seem to fold by a simple process explicable by conventional chemical
kinetics and transition-state theory. This assumes an instant equilibrium between reactants …

Stimulated endothelial cells and activated platelets express P-selectin (CD62P), a member
of the selectin family of cell adhesion molecules, which interacts with P-selectin glycoprotein …