Mammary glands of women, female dogs and female rats: similarities and differences to be considered in breast cancer research

T Ferreira, A Gama, F Seixas, AI Faustino-Rocha… - Veterinary …, 2023 - mdpi.com
Simple Summary Breast cancer research is frequently performed using a variety of models,
including animal models, in an attempt to provide information that can be translated into …

α-Mangostin nanoparticles cytotoxicity and cell death modalities in breast cancer cell lines

Y Herdiana, N Wathoni, S Shamsuddin, M Muchtaridi - Molecules, 2021 - mdpi.com
α-Mangostin (AMG) is a potent anticancer xanthone that was discovered in mangosteen
(Garcinia mangostana Linn.). AMG possesses the highest opportunity for chemopreventive …

Liquid biopsy as a diagnostic and prognostic tool for women and female dogs with breast Cancer

J Colombo, MG Moschetta-Pinheiro, AA Novais… - Cancers, 2021 - mdpi.com
Simple Summary Breast cancer (BC) has common characteristics in women and female
dogs, such as high recurrence, metastasis, and mortality rate. In both species, BC prognosis …

Comparison of PLA-based micelles and microspheres as carriers of epothilone B and rapamycin. The effect of delivery system and polymer composition on drug …

K Jelonek, A Zajdel, A Wilczok, B Kaczmarczyk… - Pharmaceutics, 2021 - mdpi.com
Co-delivery of epothilone B (EpoB) and rapamycin (Rap) increases cytotoxicity against
various kinds of cancers. However, the current challenge is to develop a drug delivery …

Leveraging single-cell transcriptomic data to uncover immune suppressive cancer cell subsets in triple-negative canine breast cancers

MC Kim, N Borcherding, WJ Song, R Kolb… - Frontiers in Veterinary …, 2024 - frontiersin.org
Introduction Single-cell RNA sequencing (scRNA-seq) has become an essential tool for
uncovering the complexities of various physiological and immunopathological conditions in …

Canine mammary neoplasia induces variations in the peripheral blood levels of CD20, CD45RA, and CD99

M Galadima, I Kotova, R Schmidt, J Pastor… - International journal of …, 2023 - mdpi.com
The idea of using tumour biomarkers as diagnostic tools is progressively increasing. Of
these, serum biomarkers are of particular interest, as they can provide rapid results. In the …

Diagnosis of Canine Tumours and the Value of Combined Detection of VEGF, P53, SF and NLRP3 for the Early Diagnosis of Canine Mammary Carcinoma

NY Yang, HH Zheng, C Yu, Y Ye, GH Xie - Animals, 2024 - mdpi.com
Simple Summary In recent years, canine tumours, as a common clinical disease with high
lethality, have gradually received public attention. At present, visual diagnosis, X-ray and …

Auranofin Suppresses the Growth of Canine Mammary Tumour Cells and Induces Apoptosis via the PI3K/AKT Pathway

Z Lin, R Chen, J Wang, Y Zheng, Z He… - Veterinary and …, 2024 - Wiley Online Library
Canine mammary gland tumour (CMT) is the most common spontaneous tumour in intact
female dogs and often exhibits metastases. Auranofin (AF) is a gold complex used for …

Molecular Characterization of CF33 Canine Cell Line and Evaluation of Its Ability to Respond against Infective Stressors in Sight of Anticancer Approaches

E Razzuoli, CG De Ciucis, B Chirullo, K Varello… - Veterinary …, 2022 - mdpi.com
Simple Summary Canine mammary cancer is very common and has many similarities with
human breast cancer. Risk factors, physiological and pathological behaviors, and the …

Protein Expression of PI3K/AKT/mTOR Pathway Targets Validated by Gene Expression and its Correlation with Prognosis in Canine Mammary Cancer

IFS Perossi, MM Saito, GR Varallo… - Journal of Mammary …, 2022 - Springer
Mammary cancer is the main type of neoplasia in female dogs and is considered an
adequate model for the biological and therapeutic study of cancer in women. The …