Management of psoriasis as a systemic disease: what is the evidence?

NJ Korman - British Journal of Dermatology, 2020 - academic.oup.com
Background Psoriasis is a chronic, systemic immune‐mediated disease characterized by
development of erythematous, indurated, scaly, pruritic and often painful skin plaques …

Systemic inflammation and cardiovascular comorbidity in psoriasis patients: causes and consequences

WH Boehncke - Frontiers in immunology, 2018 - frontiersin.org
Psoriasis is a common inflammatory skin disease characterized by the appearance of red
scaly plaques that can affect any part of the body. High prevalence, chronicity, disfiguration …

EuroGuiDerm Guideline on the systemic treatment of Psoriasis vulgaris–Part 1: treatment and monitoring recommendations

A Nast, C Smith, PI Spuls, G Avila Valle… - Journal of the …, 2020 - Wiley Online Library
This evidence‐and consensus‐based guideline on the treatment of psoriasis vulgaris was
developed following the EuroGuiDerm Guideline and Consensus Statement Development …

EuroGuiDerm Guideline on the systemic treatment of Psoriasis vulgaris–Part 2: specific clinical and comorbid situations

A Nast, C Smith, PI Spuls, G Avila Valle… - Journal of the …, 2021 - Wiley Online Library
This evidence‐and consensus‐based guideline on the treatment of psoriasis vulgaris was
developed following the EuroGuiDerm Guideline and Consensus Statement Development …

Psoriasis and metabolic syndrome: implications for the management and treatment of psoriasis

JJ Wu, A Kavanaugh, MG Lebwohl… - Journal of the …, 2022 - Wiley Online Library
Psoriasis is a chronic systemic inflammatory disorder associated with several comorbidities
in addition to the characteristic skin lesions. Metabolic syndrome (MetS) is the most frequent …

Psoriasis as an immune-mediated and inflammatory systemic disease: from pathophysiology to novel therapeutic approaches

A Campanati, A Marani, E Martina, F Diotallevi, G Radi… - Biomedicines, 2021 - mdpi.com
Psoriasis is an immune-mediated inflammatory disease, with a chronic relapsing-remitting
course, which affects 2–3% of the worldwide population. The progressive acquisitions of the …

Effects of secukinumab on metabolic and liver parameters in plaque psoriasis patients

S Gerdes, A Pinter, C Papavassilis… - Journal of the …, 2020 - Wiley Online Library
Background Psoriasis is associated with metabolic, liver and cardiovascular comorbidity.
Secukinumab, a fully human monoclonal antibody that selectively neutralizes interleukin …

Study of skin barrier function in psoriasis: the impact of emollients

D Maroto-Morales, T Montero-Vilchez… - Life, 2021 - mdpi.com
Psoriasis is a chronic multi-systemic inflammatory disease that affects the epidermal barrier.
Emollients can be used as a coadjutant therapy for psoriasis management, but little is known …

Oxidative stress induced by high salt diet—possible implications for development and clinical manifestation of cutaneous inflammation and endothelial dysfunction in …

I Krajina, A Stupin, M Šola, M Mihalj - Antioxidants, 2022 - mdpi.com
Although oxidative stress is recognized as an important effector mechanism of the immune
system, uncontrolled formation of reactive oxygen and nitrogen species promotes excessive …

Biologics for reducing cardiovascular risk in psoriasis patients

H Terui, Y Asano - Journal of Clinical Medicine, 2023 - mdpi.com
Psoriasis is a chronic inflammatory skin disease with a high prevalence of cardiovascular
disease (CVD), obesity, dyslipidemia, hypertension, diabetes mellitus, and metabolic …