Astrocytes, members of the glial family, interact through the exchange of soluble factors or by
directly contacting neurons and other brain cells, such as microglia and endothelial cells …

Brain endothelial cells are unique among endothelial cells in that they express apical
junctional complexes, including tight junctions, which quite resemble epithelial tight …

Nature has developed materials that are integrated and effective at controlling their
properties of adhesiveness and cohesiveness; the chemistry of these materials has been …

Regenerative processes occurring under physiological (maintenance) and pathological
(reparative) conditions are a fundamental part of life and vary greatly among different …

Nowadays, the research on NPC transplantation in neurological disorders is advancing on
two different fronts: on one hand, recent preclinical data are uncovering the molecular basis …

Objective Transplanted neural stem/precursor cells (NPCs) display peculiar therapeutic
plasticity in vivo. Although the replacement of cells was first expected as the prime …

Drug delivery to the brain is greatly hampered by the presence of the blood–brain barrier
(BBB) which tightly regulates the passage of molecules from blood to brain and vice versa …

Advances in stem cell biology have raised great expectations that diseases and injuries of
the central nervous system (CNS) may be ameliorated by the development of non …

Natural biomaterials are well positioned to play a significant role in the development of the
next generation of biomaterials for nervous system repair. These materials are derived from …

Currently, researchers are using neural stem cell transplantation to promote regeneration
after peripheral nerve injury, as neural stem cells play an important role in peripheral nerve …