[HTML][HTML] Pleotropic effects of polyphenols in cardiovascular system
Numerous epidemiological and clinical studies demonstrate the beneficial effects of
naturally occurring, polyphenol supplementations, on cardiovascular system. The present …
naturally occurring, polyphenol supplementations, on cardiovascular system. The present …
Natural products targeting liver X receptors or farnesoid X receptor
J She, T Gu, X Pang, Y Liu, L Tang… - Frontiers in …, 2022 - frontiersin.org
Nuclear receptors (NRs) are a superfamily of transcription factors induced by ligands and
also function as integrators of hormonal and nutritional signals. Among NRs, the liver X …
also function as integrators of hormonal and nutritional signals. Among NRs, the liver X …
[PDF][PDF] Inhibition of Adenosine Monophosphate–Activated Protein Kinase–3‐Hydroxy‐3‐Methylglutaryl Coenzyme A Reductase Signaling Leads to …
Adenosine monophosphate–activated protein kinase (AMPK) regulates multiple signaling
pathways involved in glucose and lipid metabolism in response to changes in hormonal and …
pathways involved in glucose and lipid metabolism in response to changes in hormonal and …
The role of nuclear receptors in the pathophysiology, natural course, and drug treatment of NAFLD in humans
S Ballestri, F Nascimbeni, D Romagnoli, E Baldelli… - Advances in …, 2016 - Springer
Nonalcoholic fatty liver disease (NAFLD) describes steatosis, nonalcoholic steatohepatitis
with or without fibrosis, and hepatocellular carcinoma, namely the entire alcohol-like …
with or without fibrosis, and hepatocellular carcinoma, namely the entire alcohol-like …
Impact of schisandrachinensis bee pollen on nonalcoholic fatty liver disease and gut microbiota in highfat diet induced obese mice
N Cheng, S Chen, X Liu, H Zhao, W Cao - Nutrients, 2019 - mdpi.com
Schisandrachinensis bee pollen has been used as a health food in China for centuries;
however, its bioactive constituents and functions are not very clear. In this study, we …
however, its bioactive constituents and functions are not very clear. In this study, we …
[HTML][HTML] Black rice (Oryza sativa L.) reduces obesity and improves lipid metabolism in C57BL/6J mice fed a high-fat diet
D Liu, Y Ji, J Zhao, H Wang, Y Guo, H Wang - Journal of Functional Foods, 2020 - Elsevier
To investigate the effects of dietary supplementation of WGBR on lipid metabolism,
C57BL/6J mice were fed a normal chow diet, a high-fat diet based on corn starch, a high-fat …
C57BL/6J mice were fed a normal chow diet, a high-fat diet based on corn starch, a high-fat …
[HTML][HTML] Biological mechanisms and related natural modulators of liver X receptor in nonalcoholic fatty liver disease
M Ni, B Zhang, J Zhao, Q Feng, J Peng, Y Hu… - Biomedicine & …, 2019 - Elsevier
Nonalcoholic fatty liver disease (NAFLD) is becoming a worldwide health problem, but no
approved medical treatment exists so far. Nuclear receptors are one of the drug targets for …
approved medical treatment exists so far. Nuclear receptors are one of the drug targets for …
Effects of resveratrol, exercises and their combination on Farnesoid X receptor, Liver X receptor and Sirtuin 1 gene expression and apoptosis in the liver of elderly rats …
A Hajighasem, P Farzanegi, Z Mazaheri… - PeerJ, 2018 - peerj.com
Background Non-alcoholic fatty liver disease (NAFLD) is the most common chronic liver
disorder. This study aims to consider effects of resveratrol, exercise and their combination on …
disorder. This study aims to consider effects of resveratrol, exercise and their combination on …
Sesamin ameliorates hepatic steatosis and inflammation in rats on a high-fat diet via LXRα and PPARα
R Zhang, Y Yu, S Hu, J Zhang, H Yang, B Han… - Nutrition Research, 2016 - Elsevier
Nonalcoholic fatty liver disease (NAFLD) is defined by a nonalcohol relevant pathological
accumulation of fat in the liver. Previous studies have shown that sesamin exerts antioxidant …
accumulation of fat in the liver. Previous studies have shown that sesamin exerts antioxidant …
Selective targeting of nuclear receptor FXR by avermectin analogues with therapeutic effects on nonalcoholic fatty liver disease
Non-alcoholic fatty liver disease (NAFLD) has become a predictive factor of death from many
diseases. Farnesoid X receptor (FXR) is an ideal target for NAFLD drug development due to …
diseases. Farnesoid X receptor (FXR) is an ideal target for NAFLD drug development due to …