Natural bicyclic sesquiterpenes, β‐caryophyllene (BCP) and β‐caryophyllene oxide (BCPO),
are present in a large number of plants worldwide. Both BCP and BCPO (BCP (O)) possess …

Nerolidol (3, 7, 11-trimethyl-1, 6, 10-dodecatrien-3-ol) is a naturally occurring sesquiterpene
alcohol that is present in various plants with a floral odor. It is synthesized as an intermediate …

Egyptian hieroglyphs, Chinese scrolls, and Ayurvedic literature record physicians
administering aromatic oils to their patients. Today society looks to science to document …

Pain prevalence among adults in the United States has increased 25% over the past two
decades, resulting in high health-care costs and impacts to patient quality of life. In the last …

Cellular inflammation has been recognized as the leading factor in numerous diseases,
causing either cell death, organ-specific damage, or genesis of different cancers. Icariin, a …

Background Parkinson disease (PD) is a movement disorder affecting 1% of people over the
age of 60. The etiology of the disease is unknown; however, accumulating evidence …

Pain is an unpleasant sensation associated with a wide range of injuries and diseases, and
affects approximately 20% of adults in the world. The discovery of new and more effective …

Background The Opuntia spp. have been used in traditional medicine for many centuries. It
is used in the management of diseases that involves oxidative stress, especially diabetes …

Nerolidol, an acyclic sesquiterpene found as a major constituent of several essential oils,
has several pharmacological activities, but its action in pain processes has never been …

Peperomia Ruiz and Pav, the second largest genus of the Piperaceae, has over the years
shown potential biological activities. In this sense, the present work aimed to carry out a …