Digoxin is 75% to 85% absorbed when administered orally; little is metabolized, and it is
excreted in the urine principally unchanged. Optimum digoxin serum levels are 0.5 to 2.5 …

The absorption of oral digoxin preparations has been a topic of much concern during the last
5 yean. The completeness of digoxin absorption is proportional to the area under the serum …

In an eight-subject two-way crossover study, 0.5-mg oral doses of digoxin were administered
as two 0.25-mg tablets made by two different manufacturers. Treatment" B" yielded average …

Three subjects were first given a digoxin tablet in the fasting state and subsequently
received the same formulation in the fed state, to simulate a spurious oral bioavailability …

Though established quality control standards were maintained, the bioavailability of digoxin
from Lanoxin tablets produced in the United Kingdom fell in 1969, and was restored in 1972 …

Methods Data for IV doses of digoxin in euthyroid patients presented in Figures la and lb
and in Table II of the paper by Doherty and Perkins• were fitted to the two term exponential …

In this paper, the interpretation of averaged pharmacological effect data for the cardiac
glycoside digoxin is reconsidered through a comparison with theoretically simulated data …

In a randomized crossover study the bioavailability of a single dose of digoxin and of beta-
methyl-digoxin tablets was tested in four normal volunteers. No difference was found …

Bei 6 gesunden Versuchspersonen wurde die biologische Verfügbarkeit von Digoxin und
von zwei Digoxin-Kombinationspräparaten (Theophyllin-Theobromin-Digoxin …

United States product (treatmentA) is not fully available as evidenced by the difference in
plasma levels ob، served following oral administration of that tablet and the drug dissolved …