It remains unknown how fine particulate matter (PM2. 5) constituents affect differently the
fractional concentration of exhaled nitric oxide (FeNO, a biomarker of airway inflammation) …

BACKGROUND: Inducible nitric oxide synthase (iNOS; encoded by nitric oxide synthase
isoform 2 [NOS2]) is the major enzyme for nitric oxide synthesis in airways. As such …

Background Fractional exhaled nitric oxide (F eno) is used clinically as a biomarker of
eosinophilic airway inflammation. Awareness of the factors influencing F eno values is …

Rationale: Genetic variation in arginase (ARG) and nitric oxide synthase (NOS) has been
associated with exhaled nitric oxide (FeNO) levels in children. Little is known about whether …

Fractional exhaled nitric oxide (FeNO) is a non‐invasive marker of airway inflammation in
asthma and respiratory allergy. Environmental factors, especially indoor and outdoor air …

Inducible nitric oxide synthase (NOS2) and endothelial nitric oxide synthase (NOS3) gene
play important roles in the susceptibility to type 2 diabetes mellitus (T2DM). The present …

BACKGROUND: Exposure to tobacco smoke is a well-known risk factor for childhood
asthma and reduced lung function, but the effect on airway inflammation in preschool-aged …

This study was undertaken to establish reference values of exhaled nitric oxide fraction (F
eNO) and its determinants in healthy Asian children. 693 healthy Asian children aged 5–18 …

Arginase 1 and Arginase 2 are homologous enzymes that convert l-Arginine to Urea and l-
ornithine and compete with nitric oxide synthases for l-Arginine. Increased Arginase 1 and 2 …

Background The nitric oxide (NO) pathway is involved in asthma, and eosinophils participate
in the regulation of the NO pool in pulmonary tissues. We investigated associations between …