Based on many cell culture, animal and human studies, it is well known that the most
challenge issue for developing polyphenolics as chemoprevention or anti-diabtetic agents is …

The contribution of natural products to the drug-discovery pipeline has been remarkable
since they have served as a rich source for drug development and discovery. Natural …

Resveratrol has emerged as a leading candidate for improving healthspan through
potentially slowing the aging process and preventing chronic diseases. The poor …

In recent years, a great deal of attention has been paid to natural compounds due to their
many biological effects. Polyphenols are a class of plant derivatives that have been widely …

Natural polyphenols are organic chemicals which contain phenol units in their structures.
They show antitumor properties. However, a key problem is their short half-life and low …

Simple Summary Phytoestrogens are compounds derived from plants that have a similar
structure to human sex hormones. This has led to the observation that phytoestrogens have …

Tectorigenin is a well-known natural flavonoid aglycone and an active component that exists
in numerous plants. Growing evidence suggests that tectorigenin has multiple …

Abstract Resveratrol (3, 5, 4′-trihydroxy-trans-stilbene) is a natural polyphenolic compound
that exists in Polygonum cuspidatum, grapes, peanuts and berries, as well as their …

Pain represents an unpleasant sensation linked to actual or potential tissue damage. In the
early phase, the sensation of pain is caused due to direct stimulation of the sensory nerve …

Prodrugs of resveratrol are under development. Among the long‐term goals, still largely
elusive, are (1) modulating physical properties (eg, water‐soluble derivatives bearing …