Although indentation experiments have long been used to measure the hardness and
Young's modulus, the utility of this technique in analyzing the complete elastic–plastic …

The tissue-level Young's modulus of trabecular bone is important for detailed mechanical
analysis of bone and bone-implant mechanical interactions. However, the heterogeneity and …

Scoliosis, an abnormal curvature of the human spinal column, is characterized by a lateral
deviation of the spine, accompanied by axial rotation of the vertebrae. Adolescent Idiopathic …

Osteogenesis imperfecta is a systemic heritable disorder of connective tissue whose
cardinal manifestation is bone fragility. In approximately 90% of individuals with …

The use of nanoindentation to determine nanomechanical properties of mineralized tissues
has been investigated extensively. A detailed, critical, and comprehensive review of this …

Adequate bone substitutes osseointegration has been difficult to achieve in osteoporosis.
Hydroxyapatite of the osteoporotic bone, secreted by pathologic osteoblasts, had a smaller …

The utilization of nanotechnology has brought about notable advancements in the field of
pediatric medicine, providing novel approaches for drug delivery, disease diagnosis, and …

This review is summarizing the results obtained from atomic force microscopy (AFM) and
nanoindentation experiments to date. The combination of both techniques is especially …

Osteogenesis imperfecta (OI) is an uncommon genetic bone disease associated with brittle
bones and fractures in children and adults. Although OI is most commonly associated with …

Despite general belief that the mechanical properties of bone material contribute to whole
bone strength, it is still obscure what the age effects are on mechanical behavior of the bone …