Nanoformulation strategies for improving intestinal permeability of drugs: A more precise look at permeability assessment methods and pharmacokinetic properties …

D Babadi, S Dadashzadeh, M Osouli… - Journal of controlled …, 2020 - Elsevier
The therapeutic efficacy of orally administered drugs is often restricted by their inherent
limited oral bioavailability. Low water solubility, limited permeability through the intestinal …

Development of mushroom polysaccharide and probiotics based solid self-nanoemulsifying drug delivery system loaded with curcumin and quercetin to improve their …

R Khursheed, SK Singh, S Wadhwa, M Gulati… - International Journal of …, 2021 - Elsevier
The role of mushroom polysaccharides and probiotics as pharmaceutical excipients for
development of nanocarriers has never been explored. In the present study an attempt has …

Enhanced oral bioavailability and neuroprotective effect of fisetin through its SNEDDS against rotenone-induced Parkinson's disease rat model

R Kumar, R Kumar, N Khurana, SK Singh… - Food and Chemical …, 2020 - Elsevier
Fisetin (FS) was reported to have various pharmacological activities. But due to its lower
aqueous solubility and oral bioavailability, it is not in much use. As solubility and …

Polysaccharide, fecal microbiota, and curcumin-based novel oral colon-targeted solid self-nanoemulsifying delivery system: Formulation, characterization, and in-vitro …

L Corrie, M Gulati, A Awasthi, S Vishwas, J Kaur… - Materials Today …, 2022 - Elsevier
The use of polysaccharides in preparation of microbially triggered colon-targeted delivery
system has been explored extensively to deliver drugs at the colonic site. This type of …

Exploring role of probiotics and Ganoderma lucidum extract powder as solid carriers to solidify liquid self-nanoemulsifying delivery systems loaded with curcumin

R Khursheed, SK Singh, S Wadhwa, M Gulati… - Carbohydrate …, 2020 - Elsevier
Solid self-nanoemulsifying drug delivery system (S-SENDDS) containing Curcumin (CRM)
were prepared using combination of Ganoderma lucidum extract powder (GLEP) and …

Modified apple polysaccharide capped gold nanoparticles for oral delivery of insulin

Y Kumari, SK Singh, R Kumar, B Kumar, G Kaur… - International journal of …, 2020 - Elsevier
The study entailed formulation of gold nanoparticles (AuNPs) upon reduction of chloroauric
acid by modified apple polysaccharide (MAP). AuNPs were conjugated with insulin (INS) for …

Self-nanoemulsifying composition containing curcumin, quercetin, Ganoderma lucidum extract powder and probiotics for effective treatment of type 2 diabetes mellitus …

R Khursheed, SK Singh, B Kumar, S Wadhwa… - International Journal of …, 2022 - Elsevier
Liquid self-nanoemulsifying drug delivery system (L-SNEDDS) of curcumin and quercetin
were prepared by dissolving them in isotropic mixture of Labrafil M1944CS®, Capmul …

Self-nanoemulsifying drug delivery system of fisetin: Formulation, optimization, characterization and cytotoxicity assessment

R Kumar, R Khursheed, R Kumar, A Awasthi… - Journal of drug delivery …, 2019 - Elsevier
Fisetin is a plant derived flavonoid that possesses anti-cancer, anti-oxidant and anti-
Parkinson's activities. However, due to its lipophilicity it suffers from dissolution rate limited …

Overcoming the dissolution rate, gastrointestinal permeability and oral bioavailability of glimepiride and simvastatin co-delivered in the form of nanosuspension and …

NK Pandey, SK Singh, M Gulati, B Kumar… - Journal of Drug Delivery …, 2020 - Elsevier
Simvastatin (SIM) and glimepiride (GLM) were co-formulated into nanosuspensions and self-
nanoemulsifying drug delivery systems (SNEDDS) to improve their dissolution rate and oral …

Designing and development of omega-3 fatty acid based self-nanoemulsifying drug delivery system (SNEDDS) of docetaxel with enhanced biopharmaceutical …

A Chaudhuri, N Shrivastava, S Kumar, AK Singh… - Journal of Drug Delivery …, 2022 - Elsevier
Self-nanoemulsifying drug delivery system (SNEDDS) is an encouraging nanoplatforms
fabricated to increase the oral bioavailability of poorly-bioavailable drugs. The current study …