Manufacturing the multiscale vascular hierarchy: progress toward solving the grand challenge of tissue engineering
In human vascular anatomy, blood flows from the heart to organs and tissues through a
hierarchical vascular tree, comprising large arteries that branch into arterioles and further …
hierarchical vascular tree, comprising large arteries that branch into arterioles and further …
[HTML][HTML] 3D engineered tissue models for studying human-specific infectious viral diseases
Viral infections cause damage to various organ systems by inducing organ-specific
symptoms or systemic multi-organ damage. Depending on the infection route and virus type …
symptoms or systemic multi-organ damage. Depending on the infection route and virus type …
Bio-inspired microvascular patches with MSC encapsulation for wound healing
Mesenchymal stem cells (MSCs) have been studied extensively for promoting wound
healing, while their practical applications remain challenging due to the difficulty of …
healing, while their practical applications remain challenging due to the difficulty of …
Bioengineering of high cell density tissues with hierarchical vascular networks for ex vivo whole organs
P Wu, H Asada, M Hakamada… - Advanced Materials, 2023 - Wiley Online Library
The development of tissue‐like structures such as cell sheets, spheroids, and organoids has
contributed to progress in regenerative medicine. Simultaneous achievement of scale up …
contributed to progress in regenerative medicine. Simultaneous achievement of scale up …
Engineering pre-vascularized 3D tissue and rapid vascular integration with host blood vessels via co-cultured spheroids-laden hydrogel
Recent advances in regenerative medicine and tissue engineering have enabled the
biofabrication of three-dimensional (3D) tissue analogues with the potential for use in …
biofabrication of three-dimensional (3D) tissue analogues with the potential for use in …
3D printed microfluidics for cell biological applications
L Zhao, X Wang - TrAC Trends in Analytical Chemistry, 2023 - Elsevier
Over past decades, microfluidics has been proven to be a valuable tool for cell biological
research due to several merits, including size compatibility with cells, controllability with …
research due to several merits, including size compatibility with cells, controllability with …
Engineered vasculature for cancer research and regenerative medicine
Engineered human tissues created by three-dimensional cell culture of human cells in a
hydrogel are becoming emerging model systems for cancer drug discovery and …
hydrogel are becoming emerging model systems for cancer drug discovery and …
A Transwell-Based Vascularized Model to Investigate the Effect of Interstitial Flow on Vasculogenesis
P Deng, M Zhao, X Zhang, J Qin - Bioengineering, 2022 - mdpi.com
Interstitial flow plays a significant role in vascular system development, mainly including
angiogenesis and vasculogenesis. However, compared to angiogenesis, the effect of …
angiogenesis and vasculogenesis. However, compared to angiogenesis, the effect of …
Passive-Flow-Based MPS: Emerging Physiological Flow-Mimetic Platforms for Studying Effects of Flow on Single Tissues and Inter-tissue Interactions
Flow at various scales, such as perfusion flow and interstitial flow, is a critical component of
the physiology of living systems. Microphysiological system (MPS), which is designed to …
the physiology of living systems. Microphysiological system (MPS), which is designed to …
Moving lab-grown tissues into the clinic: organ-on-a-chip and bioengineered skin systems
CA Reed-McBain, JD Patel… - Frontiers in Lab on a …, 2024 - frontiersin.org
For patients with end stage organ failure, organ transplant is frequently the only curative
option available. However, organs available for transplant are in critically short supply …
option available. However, organs available for transplant are in critically short supply …