Primer, pipelines, parameters: issues in 16S rRNA gene sequencing

I Abellan-Schneyder, MS Matchado, S Reitmeier… - Msphere, 2021 - Am Soc Microbiol
Short-amplicon 16S rRNA gene sequencing is currently the method of choice for studies
investigating microbiomes. However, comparative studies on differences in procedures are …

[HTML][HTML] Early gut microbiota intervention in premature infants: Application perspectives

Q Xiang, X Yan, W Shi, H Li, K Zhou - Journal of Advanced Research, 2023 - Elsevier
Background Preterm birth is the leading cause of death in children under the age of five.
One of the major factors contributing to the high risk of diseases and deaths in premature …

Breast milk-derived human milk oligosaccharides promote Bifidobacterium interactions within a single ecosystem

MAE Lawson, IJ O'Neill, M Kujawska… - The ISME …, 2020 - academic.oup.com
Diet-microbe interactions play an important role in modulating the early-life microbiota, with
Bifidobacterium strains and species dominating the gut of breast-fed infants. Here, we …

Early-life exposures and the microbiome: implications for IBD prevention

L Zhang, M Agrawal, SC Ng, T Jess - Gut, 2024 - gut.bmj.com
The early-life period is one of microbiome establishment and immune maturation. Early-life
exposures are increasingly being recognised to play an important role in IBD risk. The …

[HTML][HTML] Microbiota supplementation with Bifidobacterium and Lactobacillus modifies the preterm infant gut microbiota and metabolome: an observational study

C Alcon-Giner, MJ Dalby, S Caim, J Ketskemety… - Cell Reports …, 2020 - cell.com
Supplementation with members of the early-life microbiota as" probiotics" is increasingly
used in attempts to beneficially manipulate the preterm infant gut microbiota. We performed …

Rapid MinION profiling of preterm microbiota and antimicrobial-resistant pathogens

RM Leggett, C Alcon-Giner, D Heavens, S Caim… - Nature …, 2020 - nature.com
The MinION sequencing platform offers near real-time analysis of DNA sequence; this
makes the tool attractive for deployment in fieldwork or clinical settings. We used the MinION …

Impact of Maternal Intrapartum Antibiotics, and Caesarean Section with and without Labour on Bifidobacterium and Other Infant Gut Microbiota

YY Chen, X Zhao, W Moeder, HM Tun, E Simons… - Microorganisms, 2021 - mdpi.com
Background and Aims: Few studies consider the joint effect of multiple factors related to
birth, delivery mode, intrapartum antibiotic prophylaxis and the onset of labour, on the …

Dietary intervention using (1, 3)/(1, 6)-β-glucan, a fungus-derived soluble prebiotic ameliorates high-fat diet-induced metabolic distress and alters beneficially the gut …

K Muthuramalingam, V Singh, C Choi, SI Choi… - European Journal of …, 2020 - Springer
Purpose Western diet, rich in carbohydrates and fat, is said to be a major factor underlying
metabolic syndrome. Interventions with prebiotics, the key modulators of the gut microbiota …

[HTML][HTML] Improving causality in microbiome research: can human genetic epidemiology help?

KH Wade, LJ Hall - Wellcome open research, 2019 - ncbi.nlm.nih.gov
Evidence supports associations between human gut microbiome variation and multiple
health outcomes and diseases. Despite compelling results from in vivo and in vitro models …

Association and occurrence of bifidobacterial phylotypes between breast milk and fecal microbiomes in mother–infant dyads during the first 2 Years of life

W Yan, B Luo, X Zhang, Y Ni, F Tian - Frontiers in microbiology, 2021 - frontiersin.org
Breast milk acts as an intermediary for the transfer of functionally important commensal
bacteria from mother to infant, especially for Bifidobacterium that can colonize the infant gut …