Hypoalbuminemia and clinical outcomes: what is the mechanism behind the relationship?

S Kim, SA McClave, RG Martindale… - The American …, 2017 - journals.sagepub.com
Albumin has a number of important physiologic functions, which include maintaining oncotic
pressure, transporting various agents (fatty acids, bile acids, cholesterol, metal ions, and …

Albumin administration in the acutely ill: what is new and where next?

JL Vincent, JA Russell, M Jacob, G Martin, B Guidet… - Critical Care, 2014 - Springer
Albumin solutions have been used worldwide for the treatment of critically ill patients since
they became commercially available in the 1940s. However, their use has become the …

Protein-based nanoparticles for drug delivery purposes

AL Martínez-López, C Pangua, C Reboredo… - International journal of …, 2020 - Elsevier
Proteins represent a group of biopolymers with interesting properties to be employed as raw
materials in the preparation of nanoparticles for drug delivery purposes. Due to the inherent …

[HTML][HTML] Overview of albumin and its purification methods

R Raoufinia, A Mota, N Keyhanvar, F Safari… - Advanced …, 2016 - ncbi.nlm.nih.gov
As the most frequent plasma protein, albumin constitutes more than 50% of the serum
proteins in healthy individuals. It has a key role in oncotic pressure maintenance and it is …

Impaired albumin function: a novel potential indicator for liver function damage?

L Sun, H Yin, M Liu, G Xu, X Zhou, P Ge… - Annals of …, 2019 - Taylor & Francis
Albumin is the most abundant plasma protein and albumin infusion is commonly used.
Conventionally, the biologic and therapeutic effects of albumin have been thought to be due …

Hepatic organoids for microfluidic drug screening

SH Au, MD Chamberlain, S Mahesh, MV Sefton… - Lab on a Chip, 2014 - pubs.rsc.org
We introduce the microfluidic organoids for drug screening (MODS) platform, a digital
microfluidic system that is capable of generating arrays of individually addressable, free …

Phase II investigation of TVB-2640 (denifanstat) with bevacizumab in patients with first relapse high-grade astrocytoma

W Kelly, AE Diaz Duque, J Michalek, B Konkel… - Clinical Cancer …, 2023 - AACR
Purpose: Glioblastoma represents the most common primary brain tumor. Although
antiangiogenics are used in the recurrent setting, they do not prolong survival. Glioblastoma …

A survey of the different roles of polyoxometalates in their interaction with amino acids, peptides and proteins

M Arefian, M Mirzaei, H Eshtiagh-Hosseini… - Dalton …, 2017 - pubs.rsc.org
One of the most attractive areas in inorganic chemistry is the synthesis of polyoxometalates
(POMs) exhibiting new properties and applications. Since the impact of POMs in …

Dermal tattoo biosensors for colorimetric metabolite detection

AK Yetisen, R Moreddu, S Seifi, N Jiang… - Angewandte …, 2019 - Wiley Online Library
Tattooing is a ubiquitous body modification involving the injection of ink and/or dye pigments
into the dermis. Biosensors in the form of tattoos can be used to monitor metabolites in …

Short-and long-term tracking of anionic ultrasmall nanoparticles in kidney

X Liang, H Wang, Y Zhu, R Zhang, VC Cogger, X Liu… - ACS …, 2016 - ACS Publications
While biodistribution of nanoparticles (NPs) has been widely studied at the organ level,
relatively little is known about their disposition in organs at the cellular level, especially after …