Infantile spasms: outcome in clinical studies

R Riikonen - Pediatric neurology, 2020 - Elsevier
Children with infantile spasms are likely to have a poor outcome. Outcome measures for
infantile spasms include primary response to treatment, relapse of spasms, neurological …

Drug-resistant epilepsy and surgery

J Sheng, S Liu, H Qin, B Li… - Current …, 2018 - ingentaconnect.com
Background: Epilepsy is a chronic brain disease that is caused by various factors and
characterized by recurrent, episodic and temporary central nervous system dysfunction …

ILAE classification and definition of epilepsy syndromes with onset in neonates and infants: Position statement by the ILAE Task Force on Nosology and Definitions

SM Zuberi, E Wirrell, E Yozawitz, JM Wilmshurst… - …, 2022 - Wiley Online Library
Abstract The International League Against Epilepsy (ILAE) Task Force on Nosology and
Definitions proposes a classification and definition of epilepsy syndromes in the neonate …

Clinical Features, Neuropathology, and Surgical Outcome in Patients With Refractory Epilepsy and Brain Somatic Variants in the SLC35A2 Gene

C Barba, I Blumcke, MR Winawer, T Hartlieb, HC Kang… - Neurology, 2023 - AAN Enterprises
Background and Objectives The SLC35A2 gene, located at chromosome Xp11. 23, encodes
for a uridine diphosphate–galactose transporter. We describe clinical, genetic …

[HTML][HTML] Utility of MRI, PET, and ictal SPECT in presurgical evaluation of non-lesional pediatric epilepsy

C Juhász, F John - Seizure, 2020 - Elsevier
Children with epilepsy and normal structural MRI pose a particular challenge in localization
of epileptic foci for surgical resection. Many of these patients have subtle structural lesions …

Antiepileptic drug treatment of epilepsy in children

ANV Moosa - CONTINUUM: Lifelong Learning in Neurology, 2019 - journals.lww.com
PURPOSE OF REVIEW The treatment of epilepsy in children is highly individualized at each
and every major step in the management. This review examines various factors that modify …

Surgical and developmental outcomes of corpus callosotomy for West syndrome in patients without MRI lesions

H Baba, K Toda, T Ono, R Honda, S Baba - Epilepsia, 2018 - Wiley Online Library
Objective This retrospective study was designed to assess the impact of corpus callosotomy
(CC) in patients with intractable West syndrome (WS) without lesions on magnetic …

Strong coupling between slow oscillations and wide fast ripples in children with epileptic spasms: investigation of modulation index and occurrence rate

Y Iimura, K Jones, L Takada, I Shimizu, M Koyama… - …, 2018 - Wiley Online Library
Objective Epileptic spasms (ES) often become drug‐resistant. To reveal the
electrophysiological difference between children with ES (ES+) and without ES (ES−), we …

The missed value of underutilizing pediatric epilepsy surgery: a systematic review

CW Beatty, JP Lockrow, S Gedela, A Gehred… - Seminars in pediatric …, 2021 - Elsevier
Pediatric epilepsy surgery is underutilized. Only 1%-11% of children with drug resistant
epilepsy (DRE) undergo surgical treatment, or less than half of those estimated to benefit …

Tuber locations associated with infantile spasms map to a common brain network

AL Cohen, BPF Mulder, AK Prohl… - Annals of …, 2021 - Wiley Online Library
Objective Approximately 50% of patients with tuberous sclerosis complex develop infantile
spasms, a sudden onset epilepsy syndrome associated with poor neurological outcomes …