Mesoporous silica nanoparticles: A comprehensive review on synthesis and recent advances

R Narayan, UY Nayak, AM Raichur, S Garg - Pharmaceutics, 2018 - mdpi.com
Recent advancements in drug delivery technologies utilizing a variety of carriers have
resulted in a path-breaking revolution in the approach towards diagnosis and therapy alike …

Unravelling the enigma of siRNA and aptamer mediated therapies against pancreatic cancer

Z Liu, N Parveen, U Rehman, A Aziz, A Sheikh… - Molecular Cancer, 2023 - Springer
Pancreatic cancer (PC) is a fatal disease that has a poor 5-year survival rate. The poor
prognosis can be attributed to both troublesome detections at the initial stage, which makes …

A multifunctional nanoplatform against multidrug resistant cancer: merging the best of targeted chemo/gene/photothermal therapy

W Cheng, J Nie, N Gao, G Liu, W Tao… - Advanced Functional …, 2017 - Wiley Online Library
Synergistic therapy that combines chemo‐, gene‐, or photothermal means shows great
potential for enhancing the therapeutic effects on cancers. Tumor‐targeted nanoparticles …

Curcumin-loaded mesoporous silica nanoparticles for drug delivery: synthesis, biological assays and therapeutic potential–a review

M Iranshahy, MY Hanafi-Bojd, SH Aghili, M Iranshahi… - RSC …, 2023 - pubs.rsc.org
Curcumin-loaded mesoporous silica nanoparticles (MSNs) have shown promise as drug
delivery systems to address the limited pharmacokinetic characteristics of curcumin …

Nanoformulations for combination or cascade anticancer therapy

L Miao, S Guo, CM Lin, Q Liu, L Huang - Advanced drug delivery reviews, 2017 - Elsevier
Nanoparticle drug formulations have been extensively investigated, developed, and in some
cases, approved by the Food and Drug Administration (FDA). Synergistic combinations of …

Lipid-based oral formulation in capsules to improve the delivery of poorly water-soluble drugs

P Mohite, S Singh, A Pawar, A Sangale… - Frontiers in Drug …, 2023 - frontiersin.org
Poorly water-soluble drugs demonstrate significant challenge in pharmaceutical
development, which is linked to their limited oral bioavailability and therapeutic efficacy. To …

Mesoporous silica nanoparticles for co-delivery of drugs and nucleic acids in oncology: A review

JL Paris, M Vallet-Regí - Pharmaceutics, 2020 - mdpi.com
Mesoporous silica nanoparticles have attracted much attention in recent years as drug and
gene delivery systems for biomedical applications. Among their most beneficial features for …

Co-delivery of STAT3 siRNA and methotrexate in breast cancer cells

Z Shakeran, J Varshosaz, M Keyhanfar… - Artificial Cells …, 2022 - Taylor & Francis
Co-delivery of anticancer drugs and biologics can provide synergetic effects and outperform
single delivery therapies. Here, a nanoparticle (NP) system for co-delivery of methotrexate …

Pre-clinical and clinical applications of small interfering RNAs (siRNA) and co-delivery systems for pancreatic cancer therapy

S Mirzaei, MH Gholami, HL Ang, F Hashemi, A Zarrabi… - Cells, 2021 - mdpi.com
Pancreatic cancer (PC) is one of the leading causes of death and is the fourth most
malignant tumor in men. The epigenetic and genetic alterations appear to be responsible for …

Curcumin‐based nanoformulations alleviate wounds and related disorders: a comprehensive review

L Ansari, H Mashayekhi‐Sardoo… - Biofactors, 2023 - Wiley Online Library
Despite numerous advantages, curcumin's (CUR) low solubility and low bioavailability limit
its employment as a free drug. CUR‐incorporated nanoformulation enhances the …