The objective of this work is to present a review of computational tools and models for
pharmaceutical processes, specifically those for the continuous manufacture of solid dosage …

Mechanical properties play a central role in drug formulation development and
manufacturing. Traditional characterization of mechanical properties of pharmaceutical …

Material properties are known to have a significant impact on pharmaceutical manufacturing
performance, particularly for solid product processes. Evaluating the performance of a …

This study investigated deformation mechanisms of some commonly used pharmaceutical
fillers, such as microcrystalline cellulose, lactose, dicalcium phosphate, isomalt and …

Capping or lamination is an unsolved common problem in tablet manufacturing. Knowledge
gaps remain despite an enormous amount of effort made in the past to better understand the …

Highlights•A compacted model was developed to predict powder compression.•A
densification mechanism of pelletisation was developed.•Quantitative analysis of the role of …

The aim of this study was to investigate the correlation between critical granules characters
(including particle size, surface roughness, and apparent porosity) and mechanical …

The material properties of excipients and active pharmaceutical ingredients (API's) are
important parameters that affect blend uniformity of pharmaceutical powder formulations …

As one of the commonly-used solid dosage forms, pharmaceutical tablets have been widely
used to deliver active drugs into the human body, satisfying patient's therapeutic …

The three point bending method is commonly used for determining Young's modulus, E.
However, the literature E values of some common pharmaceutical excipients, determined by …