The effectiveness and safety of low-intensity transcranial ultrasound stimulation: A systematic review of human and animal studies

PP Qin, M Jin, AW Xia, AS Li, TT Lin, Y Liu… - Neuroscience & …, 2024 - Elsevier
Low-intensity transcranial ultrasound stimulation (LITUS) is a novel non-invasive
neuromodulation technique. We conducted a systematic review to evaluate current evidence …

A review of functional brain differences predicting relapse in substance use disorder: Actionable targets for new methods of noninvasive brain stimulation

BC Gibson, ED Claus, J Sanguinetti… - Neuroscience & …, 2022 - Elsevier
Neuroimaging studies have identified a variety of brain regions whose activity predicts
substance use (ie, relapse) in patients with substance use disorder (SUD), suggesting that …

Effects of transcranial ultrasound stimulation pulsed at 40 Hz on Aβ plaques and brain rhythms in 5× FAD mice

M Park, GM Hoang, T Nguyen, E Lee, HJ Jung… - Translational …, 2021 - Springer
Background Alzheimer's disease (AD) is the most common cause of dementia, and is
characterized by amyloid-β (Aβ) plaques and tauopathy. Reducing Aβ has been considered …

Ultrasound: A new strategy for artificial synapses modulation

J Yuan, Y Li, M Wang, X Huang, T Zhang, KH Xue… - InfoMat, 2024 - Wiley Online Library
Due to its non‐invasive nature, ultrasound has been widely used for neuromodulation in
biological systems, where its application influences the synaptic weights and the process of …

[HTML][HTML] Noninvasive ultrasound deep brain stimulation for the treatment of Parkinson's disease model mouse

H Zhou, L Niu, L Meng, Z Lin, J Zou, X Xia, X Huang… - Research, 2019 - spj.science.org
Modulating basal ganglia circuitry is of great significance in the improvement of motor
function in Parkinson's disease (PD). Here, for the first time, we demonstrate that …

Low-intensity focused ultrasound ameliorates depression-like behaviors associated with improving the synaptic plasticity in the vCA1-mPFC pathway

F Wang, Q Cai, R Ju, S Wang, L Liu, M Pan… - Cerebral …, 2023 - academic.oup.com
It is of great social significance and clinical value to explore new effective treatments for
depression. Low-intensity focused ultrasound stimulation (LIFUS) has been indicated to …

Low‐intensity pulsed ultrasound ameliorates depression‐like behaviors in a rat model of chronic unpredictable stress

J Zhang, H Zhou, J Yang, J Jia, L Niu… - CNS Neuroscience …, 2021 - Wiley Online Library
Introduction There is an unmet need for better nonpharmaceutical treatments for depression.
Low‐intensity pulsed ultrasound (LIPUS) is a novel type of neuromodulation that could be …

High frequency electromagnetic radiation stimulates neuronal growth and hippocampal synaptic transmission

S Ma, Z Li, S Gong, C Lu, X Li, Y Li - Brain Sciences, 2023 - mdpi.com
Terahertz waves lie within the rotation and oscillation energy levels of biomolecules, and
can directly couple with biomolecules to excite nonlinear resonance effects, thus causing …

[HTML][HTML] Transcranial ultrasound stimulation at the peak-phase of theta-cycles in the hippocampus improve memory performance

Z Xie, S Dong, Y Zhang, Y Yuan - NeuroImage, 2023 - Elsevier
The present study aimed to investigate the effectiveness of closed-loop transcranial
ultrasound stimulation (closed-loop TUS) as a non-invasive, high temporal-spatial resolution …

[HTML][HTML] Noninvasive ultrasound stimulation of ventral tegmental area induces reanimation from general anaesthesia in mice

T Bian, W Meng, M Qiu, Z Zhong, Z Lin, J Zou, Y Wang… - Research, 2021 - spj.science.org
Evidence in animals suggests that deep brain stimulation or optogenetics can be used for
recovery from disorders of consciousness (DOC). However, these treatments require …