Glucose-6-phosphate dehydrogenase (G6PD) is the only rate-limiting enzyme in the
pentose phosphate pathway (PPP). Rapidly proliferating cells require metabolites from PPP …

Introduction Ovarian cancer (OC) is a gynecological tumor disease, which is usually
diagnosed at an advanced stage and has a poor prognosis. It has been established that the …

Metabolic reprogramming, especially reprogrammed glucose metabolism, is a well-known
cancer hallmark related to various characteristics of tumor cells, including proliferation …

Renal cell carcinoma (RCC) is one of the most lethal urological cancers, highly resistant to
chemo and radiotherapy. Obesity and smoking are the best‐known risk factors of RCC, both …

Cancer cells switch their metabolism toward glucose metabolism to sustain their
uncontrolled proliferation. Consequently, glycolytic intermediates are diverted into the …

Glucose-6-phosphate dehydrogenase (G6PD) deficiency is the most common enzymopathy
in humans. G6PD is an essential enzyme in the pentose phosphate pathway (PPP) …

Clear cell renal cell carcinoma (ccRCC) is the most common subtype of renal cell
carcinoma. Redox metabolism has been recognized as the hallmark of cancer. But the …

Genes involved in drug absorption, distribution, metabolism, and excretion (ADME) are
named ADME genes. However, the comprehensive role of ADME genes in kidney renal …

Glioblastoma multiforme (GBM) represents the deadliest tumor among brain cancers. It is a
solid tumor characterized by uncontrolled cell proliferation generating the hypoxic niches in …

Clear cell renal cell carcinoma (ccRCC) is characterized by its aggressive invasion and
metastasis, presenting significant clinical challenges. Gaining insights into the molecular …