Neuroscience of addiction: relevance to prevention and treatment
ND Volkow, M Boyle - American Journal of Psychiatry, 2018 - Am Psychiatric Assoc
Addiction, the most severe form of substance use disorder, is a chronic brain disorder
molded by strong biosocial factors that has devastating consequences to individuals and to …
molded by strong biosocial factors that has devastating consequences to individuals and to …
Oxytocin for the treatment of drug and alcohol use disorders
MR Lee, EM Weerts - Behavioural pharmacology, 2016 - journals.lww.com
There is growing interest in the use of oxytocin (OT) as a potential treatment for alcohol and
other substance-use disorders. OT is a neuropeptide that modulates adaptive processes …
other substance-use disorders. OT is a neuropeptide that modulates adaptive processes …
Rebalancing the addicted brain: oxytocin interference with the neural substrates of addiction
MT Bowen, ID Neumann - Trends in neurosciences, 2017 - cell.com
Drugs that act on the brain oxytocin (OXT) system may provide a much-needed treatment
breakthrough for substance-use disorders. Targeting the brain OXT system has the potential …
breakthrough for substance-use disorders. Targeting the brain OXT system has the potential …
Pharmacotherapeutic agents in the treatment of methamphetamine dependence
KC Morley, JL Cornish, A Faingold… - Expert opinion on …, 2017 - Taylor & Francis
Introduction: Methamphetamine use is a serious public health concern in many countries
and is second to cannabis as the most widely abused illicit drug in the world. Effective …
and is second to cannabis as the most widely abused illicit drug in the world. Effective …
The role of oxytocin in alcohol and drug abuse
The neuropeptide oxytocin (OXT) plays a key role in adaptive processes associated with
reward, tolerance, memory and stress responses. Through interactions with brain reward …
reward, tolerance, memory and stress responses. Through interactions with brain reward …
Targeting the oxytocin system to treat addictive disorders: rationale and progress to date
The neuropeptide oxytocin plays a role in reward, stress, social affiliation, learning, and
memory processes. As such, there is increasing interest in oxytocin as a potential treatment …
memory processes. As such, there is increasing interest in oxytocin as a potential treatment …
Oxytocin and rodent models of addiction
Interest for the use of oxytocin as a treatment for addiction began over 40 years ago. Better
known for its roles in parturition, lactation and pair bonding, oxytocin also has anxiolytic …
known for its roles in parturition, lactation and pair bonding, oxytocin also has anxiolytic …
The effect of chronic oxytocin treatment during abstinence from methamphetamine self-administration on incubation of craving, reinstatement, and anxiety
Methamphetamine (METH) abuse is characterised by chronic relapse and anxiety, for which
there are no effective pharmacotherapies. Acute treatment with the neuropeptide oxytocin …
there are no effective pharmacotherapies. Acute treatment with the neuropeptide oxytocin …
The impact of early life stress on the central oxytocin system and susceptibility for drug addiction: Applicability of oxytocin as a pharmacotherapy
Early life trauma is strongly associated with an increased vulnerability to abuse illicit drugs
and the impairment of neural development. This includes alterations to the development of …
and the impairment of neural development. This includes alterations to the development of …
Oxytocin signaling in the treatment of drug addiction: Therapeutic opportunities and challenges
X Che, J Cai, Y Liu, T Xu, J Yang, C Wu - Pharmacology & therapeutics, 2021 - Elsevier
Drug addiction is one of the leading causes of mortality worldwide. Despite great advances
were achieved in understanding the neurobiology of drug addiction, the therapeutic options …
were achieved in understanding the neurobiology of drug addiction, the therapeutic options …