The diversity of retrotransposons and the properties of their reverse transcriptases

TH Eickbush, VK Jamburuthugoda - Virus research, 2008 - Elsevier
A number of abundant mobile genetic elements called retrotransposons reverse transcribe
RNA to generate DNA for insertion into eukaryotic genomes. Four major classes of …

The Ty1 LTR‐Retrotransposon of Budding Yeast, Saccharomyces cerevisiae

M Joan Curcio, S Lutz, P Lesage - Mobile DNA III, 2015 - Wiley Online Library
Ty1 elements have a structure that is analogous to simple retroviruses, but they lack an
envelope gene (Fig. 1)(1). The most highly characterized Ty1 element is Ty1‐H3, which was …

Reverse transcription of retroviruses and LTR retrotransposons

M Wilhelm, FX Wilhelm - Cellular and Molecular Life Sciences CMLS, 2001 - Springer
Retroelements are mobile genetic entities that replicate via reverse transcription of a
template RNA. A key component to the life cycle of these elements is the enzyme reverse …

Binding and kinetic properties of HIV‐1 reverse transcriptase markedly differ during initiation and elongation of reverse transcription.

JM Lanchy, C Ehresmann, SF Le Grice… - The EMBO …, 1996 - embopress.org
We recently showed that primer tRNA3Lys, human immunodeficiency virus type 1 (HIV‐1)
RNA and HIV‐1 reverse transcriptase (RT) form a specific complex of initiation of reverse …

[HTML][HTML] Structural basis for the specificity of the initiation of HIV‐1 reverse transcription

C Isel, E Westhof, C Massire, SFJ Le Grice… - The EMBO …, 1999 - embopress.org
Initiation of human immunodeficiency virus type 1 (HIV‐1) reverse transcription requires
specific recognition of the viral genome, tRNA 3 Lys, which acts as primer, and reverse …

Ty1 and Ty5 of Saccharomyces cerevisiae

DF Voytas, JD Boeke - Mobile DNA II, 2007 - Wiley Online Library
Summary Ty1 and Ty5 of Saccharomyces cerevisiae are long terminal repeat (LTR)
retrotransposons, members of a large and ubiquitous class of mobile genetic elements. Like …

A New Family of Ty1-copia-Like Retrotransposons Originated in the Tomato Genome by a Recent Horizontal Transfer Event

X Cheng, D Zhang, Z Cheng, B Keller, HQ Ling - Genetics, 2009 - academic.oup.com
Rider is a novel and recently active Ty1-copia-like retrotransposon isolated from the T3238
fer mutant of tomato. Structurally, it is delimited by a duplication of target sites and contains …

The importance of the A-rich loop in human immunodeficiency virus type 1 reverse transcription and infectivity

C Liang, X Li, L Rong, P Inouye, Y Quan… - Journal of …, 1997 - Am Soc Microbiol
Nucleotide segment (+ 169) AAAA (+ 172) constitutes an A-rich loop within human
immunodeficiency virus type 1 (HIV-1)(HXB2D) RNA and is able to interact with the …

Ty3, a Position‐specific Retrotransposon in Budding Yeast

S Sandmeyer, K Patterson, V Bilanchone - Mobile DNA III, 2015 - Wiley Online Library
Long terminal repeat (LTR) retrotransposons occur throughout eukaryotic phyla, but vary
greatly in both the types of elements and the representation among species. The majority of …

Interaction of retroviral reverse transcriptase with template–primer duplexes during replication

EJ Arts, SFJ Le Grice - Progress in nucleic acid research and molecular …, 1997 - Elsevier
Conversion of the single-stranded RNA of an invading retrovirus into double-stranded
proviral DNA is catalyzed in a multi-step process by a single virus-coded enzyme, reverse …