Determinants of approved acetylcholinesterase inhibitor response outcomes in Alzheimer's disease: relevance for precision medicine in neurodegenerative diseases
Acetylcholinesterase inhibitors (ChEI) are the global standard of care for the symptomatic
treatment of Alzheimer's disease (AD) and show significant positive effects in …
treatment of Alzheimer's disease (AD) and show significant positive effects in …
Intrinsic connectome organization across temporal scales: New insights from cross-modal approaches
S Sadaghiani, J Wirsich - Network Neuroscience, 2020 - direct.mit.edu
The discovery of a stable, whole-brain functional connectivity organization that is largely
independent of external events has drastically extended our view of human brain function …
independent of external events has drastically extended our view of human brain function …
[HTML][HTML] Donepezil alone and combined with intensive language-action therapy on depression and apathy in chronic post-stroke aphasia: A feasibility study
ML Berthier, L Edelkraut, FJ López-González… - Brain and …, 2023 - Elsevier
This study explored the feasibility and effectiveness of a short-term (10-week) intervention
trial using Donepezil administered alone and combined with intensive language action …
trial using Donepezil administered alone and combined with intensive language action …
Ten key reasons for continuing research on pharmacotherapy for post-stroke aphasia
ML Berthier - Aphasiology, 2021 - Taylor & Francis
Background: Aphasia is a devastating disorder occurring in more than 30% of stroke victims.
Speech and language therapy (SLT) is the treatment of choice for post-stroke aphasia (PSA) …
Speech and language therapy (SLT) is the treatment of choice for post-stroke aphasia (PSA) …
[HTML][HTML] Vigilance effects in resting-state fMRI
TT Liu, M Falahpour - Frontiers in neuroscience, 2020 - frontiersin.org
Measures of resting-state functional magnetic resonance imaging (rsfMRI) activity have
been shown to be sensitive to cognitive function and disease state. However, there is …
been shown to be sensitive to cognitive function and disease state. However, there is …
Abnormal dynamic functional connectivity after sleep deprivation from temporal variability perspective
J Sun, R Zhao, Z He, M Chang, F Wang… - Human Brain …, 2022 - Wiley Online Library
Sleep deprivation (SD) is very common in modern society and regarded as a potential
causal mechanism of several clinical disorders. Previous neuroimaging studies have …
causal mechanism of several clinical disorders. Previous neuroimaging studies have …
[HTML][HTML] Modular slowing of resting-state dynamic functional connectivity as a marker of cognitive dysfunction induced by sleep deprivation
Abstract Dynamic Functional Connectivity (dFC) in the resting state (rs) is considered as a
correlate of cognitive processing. Describing dFC as a flow across morphing connectivity …
correlate of cognitive processing. Describing dFC as a flow across morphing connectivity …
[HTML][HTML] Neurophysiological signals as predictive translational biomarkers for Alzheimer's disease treatment: effects of donepezil on neuronal network oscillations in …
Abstract Background Translational research in Alzheimer's disease (AD) pathology provides
evidence that accumulation of amyloid-β and hyperphosphorylated tau, neuropathological …
evidence that accumulation of amyloid-β and hyperphosphorylated tau, neuropathological …
Resting state alpha electroencephalographic rhythms are affected by sex in cognitively unimpaired seniors and patients with Alzheimer's disease and amnesic mild …
In the present retrospective and exploratory study, we tested the hypothesis that sex may
affect cortical sources of resting state eyes-closed electroencephalographic (rsEEG) rhythms …
affect cortical sources of resting state eyes-closed electroencephalographic (rsEEG) rhythms …
[HTML][HTML] Alterations in cerebellar functional connectivity are correlated with decreased psychomotor vigilance following total sleep deprivation
Y Zhang, Y Yang, Y Yang, J Li, W Xin… - Frontiers in …, 2019 - frontiersin.org
Previous studies have reported significant changes in functional connectivity among various
brain networks following sleep restriction. The cerebellum plays an important role in …
brain networks following sleep restriction. The cerebellum plays an important role in …