Ultrasound molecular imaging and its applications in cancer diagnosis and therapy

G Zhang, HR Ye, Y Sun, ZZ Guo - ACS sensors, 2022 - ACS Publications
Ultrasound imaging is regarded as a highly sensitive imaging modality used in routine
clinical examinations. Over the last several decades, ultrasound contrast agents have been …

Mechanistic understanding the bioeffects of ultrasound-driven microbubbles to enhance macromolecule delivery

P Qin, T Han, CH Alfred, L Xu - Journal of controlled release, 2018 - Elsevier
Ultrasound-driven microbubbles can trigger reversible membrane perforation
(sonoporation), open interendothelial junctions and stimulate endocytosis, thereby providing …

Ultrasound‐Sensitive Intelligent Nanosystems: A Promising Strategy for the Treatment of Neurological Diseases

X Pan, W Huang, G Nie, C Wang… - Advanced Materials, 2024 - Wiley Online Library
Neurological diseases are a major global health challenge, affecting hundreds of millions of
people worldwide. Ultrasound therapy plays an irreplaceable role in the treatment of …

Highlights in ultrasound-targeted microbubble destruction-mediated gene/drug delivery strategy for treatment of malignancies

H Li, Y Zhang, H Shu, W Lv, C Su, F Nie - International Journal of …, 2022 - Elsevier
Ultrasound is one of the safest and most advanced medical imaging technologies that is
widely used in clinical practice. Ultrasound microbubbles, traditionally used for contrast …

Ultrasound contrast agents and delivery systems in cancer detection and therapy

R Perera, P Nittayacharn, M Cooley, O Jung… - Advances in Cancer …, 2018 - Elsevier
Ultrasound is the second most utilized imaging modality in the world because it is widely
accessible, robust, and safe. Aside from its extensive use in diagnostic imaging, ultrasound …

Immune/hypoxic tumor microenvironment regulation-enhanced photodynamic treatment realized by pH-responsive phase transition-targeting nanobubbles

M Zhao, X Yang, H Fu, C Chen, Y Zhang… - … applied materials & …, 2021 - ACS Publications
Due to a special pathological type of triple-negative breast cancer (TNBC) and the lack of
expression of the estrogen receptor (ER), progesterone receptor (PR), and human …

[HTML][HTML] In vivo assessment of inflammation in carotid atherosclerosis by noninvasive photoacoustic imaging

Z Xie, Y Yang, Y He, C Shu, D Chen, J Zhang… - Theranostics, 2020 - ncbi.nlm.nih.gov
Objectives: The objective of this study was to demonstrate the feasibility of using
noninvasive photoacoustic imaging technology along with novel semiconducting polymer …

[HTML][HTML] Biomedical applications of acoustically responsive phase shift nanodroplets: Current status and future directions

ALY Kee, BM Teo - Ultrasonics sonochemistry, 2019 - Elsevier
The evolution of ultrasonic contrast agents to enhance the reflectivity of structures in the
human body has consolidated ultrasound's stance as a reliable diagnostic imaging modality …

[HTML][HTML] Concurrent visual and acoustic tracking of passive and active delivery of nanobubbles to tumors

C Pellow, EC Abenojar, AA Exner, G Zheng… - Theranostics, 2020 - ncbi.nlm.nih.gov
Background: There has been growing interest in nanobubbles for their potential to extend
bubble-mediated ultrasound approaches beyond that of their larger microbubble …

Improving performance of nanoscale ultrasound contrast agents using N, N-diethylacrylamide stabilization

RH Perera, H Wu, P Peiris, C Hernandez… - … , Biology and Medicine, 2017 - Elsevier
The design of nanoscale yet highly echogenic agents for imaging outside of the vasculature
and for ultrasound-mediated drug delivery remains a formidable challenge. We have …