T cell-based adoptive cell therapy (ACT) has emerged as a promising treatment for various
diseases, particularly cancers. Unlike other immunotherapy modalities, ACT involves directly …

Breakthroughs in actual clinical applications have begun through vaccine-based cancer
immunotherapy, which uses the body's immune system, both humoral and cellular, to attack …

CAR T cell therapy has achieved remarkable clinical success for the treatment of
hematological malignancies. However, producing these bespoke cancer‐killing cells is a …

Adoptive T cell therapy (ACT) has achieved remarkable results in the treatment of cancer.
Tumor‐antigen specific T cells are the main players in the clearance of cancerous cells, but …

Cancer immunotherapy has made tremendous advancements in treating various
malignancies. The biggest hurdle to successful immunotherapy would be the …

Polymeric nanoparticles (NPs) are widely used as drug delivery systems in nanomedicine.
Despite their widespread application, a comprehensive understanding of their intracellular …

Abstract Antigen‐presenting cells (APCs), such as dendritic cells and macrophages, have a
unique ability to survey the body and present information to T cells via peptide‐loaded major …

The dendritic cell (DC)‐T cell axis is a bridge that connects innate and adaptive immunities.
The initial immune response against tumors is mainly induced by mature antigen‐presenting …

Chimeric antigen receptor T (CAR-T) cell therapy has significantly transformed the
management of cancer, specifically in patients suffering from leukemia and lymphoma. This …