Mechanisms of synaptic transmission dysregulation in the prefrontal cortex: pathophysiological implications
The prefrontal cortex (PFC) serves as the chief executive officer of the brain, controlling the
highest level cognitive and emotional processes. Its local circuits among glutamatergic …
highest level cognitive and emotional processes. Its local circuits among glutamatergic …
Circuit organization of the rodent medial prefrontal cortex
PG Anastasiades, AG Carter - Trends in neurosciences, 2021 - cell.com
The prefrontal cortex (PFC) orchestrates higher brain function and becomes disrupted in
many mental health disorders. The rodent medial PFC (mPFC) possesses an enormous …
many mental health disorders. The rodent medial PFC (mPFC) possesses an enormous …
Single-neuron projectome of mouse prefrontal cortex
Prefrontal cortex (PFC) is the cognitive center that integrates and regulates global brain
activity. However, the whole-brain organization of PFC axon projections remains poorly …
activity. However, the whole-brain organization of PFC axon projections remains poorly …
Striatal circuits for reward learning and decision-making
The striatum is essential for learning which actions lead to reward and for implementing
those actions. Decades of experimental and theoretical work have led to several influential …
those actions. Decades of experimental and theoretical work have led to several influential …
Cortical ensembles orchestrate social competition through hypothalamic outputs
Most social species self-organize into dominance hierarchies,, which decreases aggression
and conserves energy,, but it is not clear how individuals know their social rank. We have …
and conserves energy,, but it is not clear how individuals know their social rank. We have …
Signalling pathways in autism spectrum disorder: mechanisms and therapeutic implications
CC Jiang, LS Lin, S Long, XY Ke, K Fukunaga… - Signal transduction and …, 2022 - nature.com
Autism spectrum disorder (ASD) is a prevalent and complex neurodevelopmental disorder
which has strong genetic basis. Despite the rapidly rising incidence of autism, little is known …
which has strong genetic basis. Despite the rapidly rising incidence of autism, little is known …
Prefrontal–amygdala circuits in social decision-making
An increasing amount of research effort is being directed toward investigating the neural
bases of social cognition from a systems neuroscience perspective. Evidence from multiple …
bases of social cognition from a systems neuroscience perspective. Evidence from multiple …
Efficient and accurate extraction of in vivo calcium signals from microendoscopic video data
P Zhou, SL Resendez, J Rodriguez-Romaguera… - elife, 2018 - elifesciences.org
In vivo calcium imaging through microendoscopic lenses enables imaging of previously
inaccessible neuronal populations deep within the brains of freely moving animals …
inaccessible neuronal populations deep within the brains of freely moving animals …
[HTML][HTML] Correlated neural activity and encoding of behavior across brains of socially interacting animals
Social interactions involve complex decision-making tasks that are shaped by dynamic,
mutual feedback between participants. An open question is whether and how emergent …
mutual feedback between participants. An open question is whether and how emergent …
Social circuits and their dysfunction in autism spectrum disorder
Social behaviors, how individuals act cooperatively and competitively with conspecifics, are
widely seen across species. Rodents display various social behaviors, and many different …
widely seen across species. Rodents display various social behaviors, and many different …