New frontiers in time-domain diffuse optics, a review

A Pifferi, D Contini, AD Mora, A Farina… - … of biomedical optics, 2016 - spiedigitallibrary.org
The recent developments in time-domain diffuse optics that rely on physical concepts (eg,
time-gating and null distance) and advanced photonic components (eg, vertical cavity …

Diffuse optical characterization of collagen absorption from 500 to 1700 nm

SKV Sekar, I Bargigia, AD Mora… - … of biomedical optics, 2017 - spiedigitallibrary.org
Reduction in scattering, high absorption, and spectral features of tissue constituents above
1000 nm could help in gaining higher spatial resolution, penetration depth, and specificity …

Determination of reference values for optical properties of liquid phantoms based on Intralipid and India ink

L Spinelli, M Botwicz, N Zolek, M Kacprzak… - Biomedical optics …, 2014 - opg.optica.org
A multi-center study has been set up to accurately characterize the optical properties of
diffusive liquid phantoms based on Intralipid and India ink at near-infrared (NIR) …

Broadband time domain diffuse optical reflectance spectroscopy: a review of systems, methods, and applications

S Konugolu Venkata Sekar, P Lanka, A Farina… - Applied Sciences, 2019 - mdpi.com
This review presents recent developments and a wide overview of broadband time domain
diffuse optical spectroscopy (TD-DOS). Various topics including physics of photon migration …

Towards next-generation time-domain diffuse optics for extreme depth penetration and sensitivity

AD Mora, D Contini, S Arridge, F Martelli… - Biomedical optics …, 2015 - opg.optica.org
Light is a powerful tool to non-invasively probe highly scattering media for clinical
applications ranging from oncology to neurology, but also for molecular imaging, and quality …

There's plenty of light at the bottom: statistics of photon penetration depth in random media

F Martelli, T Binzoni, A Pifferi, L Spinelli, A Farina… - Scientific Reports, 2016 - nature.com
We propose a comprehensive statistical approach describing the penetration depth of light
in random media. The presented theory exploits the concept of probability density function f …

Broadband (600–1350 nm) time-resolved diffuse optical spectrometer for clinical use

SKV Sekar, A Dalla Mora, I Bargigia… - IEEE Journal of …, 2015 - ieeexplore.ieee.org
We report on the design, development, and performance assessment of a portable time-
resolved system measuring absorption and scattering spectra of highly diffusive media over …

Solid phantom recipe for diffuse optics in biophotonics applications: a step towards anatomically correct 3D tissue phantoms

SKV Sekar, A Pacheco, P Martella, H Li… - Biomedical optics …, 2019 - opg.optica.org
We present a tissue mimicking optical phantom recipe to create robust well tested solid
phantoms. The recipe consists of black silicone pigment (absorber), silica microspheres …

Structural white-matter connections mediating distinct behavioral components of spatial neglect in right brain-damaged patients

MJ Vaessen, A Saj, KO Lovblad, M Gschwind… - Cortex, 2016 - Elsevier
Spatial neglect is a neuropsychological syndrome in which patients fail to perceive and
orient to stimuli located in the space contralateral to the lesioned hemisphere. It is …

Fast silicon photomultiplier improves signal harvesting and reduces complexity in time-domain diffuse optics

AD Mora, E Martinenghi, D Contini, A Tosi, G Boso… - Optics express, 2015 - opg.optica.org
We present a proof of concept prototype of a time-domain diffuse optics probe exploiting a
fast Silicon PhotoMultiplier (SiPM), featuring a timing resolution better than 80 ps, a fast tail …