Current and emerging applications of droplet digital PCR in oncology: an updated review

S Olmedillas-López, R Olivera-Salazar… - Molecular Diagnosis & …, 2022 - Springer
In the era of personalized medicine and targeted therapies for the management of patients
with cancer, ultrasensitive detection methods for tumor genotyping, such as next-generation …

Recent advances in droplet-based microfluidic technologies for biochemistry and molecular biology

J Sánchez Barea, J Lee, DK Kang - Micromachines, 2019 - mdpi.com
Recently, droplet-based microfluidic systems have been widely used in various biochemical
and molecular biological assays. Since this platform technique allows manipulation of large …

Clinical utility of liquid biopsy-based actionable mutations detected via ddPCR

I Palacín-Aliana, N García-Romero, A Asensi-Puig… - Biomedicines, 2021 - mdpi.com
Cancer is one of the leading causes of death worldwide and remains a major public health
challenge. The introduction of more sensitive and powerful technologies has permitted the …

Next generation sequencing in cytology

P Pisapia, F Pepe, R Sgariglia, M Nacchio… - …, 2021 - Wiley Online Library
The application of next generation sequencing (NGS) technology to cytological samples has
significantly modified molecular cytopathology practice. Cytological samples represent a …

Liquid biopsy from research to clinical practice: focus on non-small cell lung cancer

U Malapelle, P Pisapia, A Addeo, O Arrieta… - Expert review of …, 2021 - Taylor & Francis
Introduction In the current era of personalized medicine, liquid biopsy has acquired a
relevant importance in patient management of advanced stage non-small cell lung cancer …

Next generation sequencing in cytopathology: focus on non-small cell lung cancer

P Pisapia, F Pepe, A Iaccarino, R Sgariglia… - Frontiers in …, 2021 - frontiersin.org
Molecular cytopathology is a rapidly evolving field embracing both conventional microscopy
and molecular pathology. Its growing popularity stems from the fact that in many types of …

CTC, ctDNA, and exosome in thyroid cancers: a review

W Wang, Z Zheng, J Lei - International journal of molecular sciences, 2023 - mdpi.com
Thyroid cancer has become more common in recent years all around the world. Many issues
still need to be urgently addressed in the diagnosis, treatment, and prognosis of thyroid …

Clinical applications of endobronchial Ultrasound (EBUS) Scope: Challenges and opportunities

D Biondini, M Tinè, U Semenzato, M Daverio… - Diagnostics, 2023 - mdpi.com
Endobronchial Ultrasound (EBUS) has been widely used to stage lung tumors and to
diagnose mediastinal diseases. In the last decade, this procedure has evolved in several …

Lung cancer cytology and small biopsy specimens: diagnosis, predictive biomarker testing, acquisition, triage, and management

S Sung, JJ Heymann, JP Crapanzano… - Journal of the American …, 2020 - Elsevier
Highlights•Morphologic and molecular subtyping of non-small cell lung carcinoma, which
must often be performed on cytologic or small histologic biopsy specimens, is necessary for …

Liquid biopsy in cancer current: status, challenges and future prospects

L Ma, H Guo, Y Zhao, Z Liu, C Wang, J Bu… - … and Targeted Therapy, 2024 - nature.com
Cancer has a high mortality rate across the globe, and tissue biopsy remains the gold
standard for tumor diagnosis due to its high level of laboratory standardization, good …