Protein energy wasting (PEW) is common in patients with chronic kidney disease (CKD) and
is associated with adverse clinical outcomes, especially in individuals receiving …

Elevated protein catabolism and protein malnutrition are common in patients with chronic
kidney disease (CKD) and end-stage renal disease (ESRD). The underlying etiology …

On December 13th and 14th a group of scientists and clinicians met in Washington, DC, for
the cachexia consensus conference. At the present time, there is no widely agreed upon …

The recent research findings concerning syndromes of muscle wasting, malnutrition, and
inflammation in individuals with chronic kidney disease (CKD) or acute kidney injury (AKI) …

Loss of skeletal muscle mass occurs during aging (sarcopenia), disease (cachexia), or
inactivity (atrophy). This article contrasts and compares the metabolic causes of loss of …

All intracellular proteins and many extracellular proteins are continually “turning over;” ie,
they are being hydrolyzed to their constituent amino acids and replaced by new synthesis …

The term uraemic myopathy has been used loosely to describe the skeletal muscle
abnormalities in uraemic patients. However, it does not fully explain the observed …

Chronic kidney disease is considered an inflammatory state and a high fiber intake is
associated with decreased inflammation in the general population. Here, we determined …

Muscle wasting is associated with a wide range of catabolic diseases. This debilitating loss
of muscle mass and functional capacity reduces the quality of life and increases the risks of …

With trauma, sepsis, cancer, or uremia, animals or patients experience accelerated
degradation of muscle protein in the ATP-ubiquitin-proteasome (Ub-P'some) system. The …