Triple threat: how diabetes results in worsened bacterial infections

BP Darwitz, CJ Genito, LR Thurlow - Infection and Immunity, 2024 - Am Soc Microbiol
Diabetes mellitus, characterized by impaired insulin signaling, is associated with increased
incidence and severity of infections. Various diabetes-related complications contribute to …

Metabolism shapes immune responses to Staphylococcus aureus

P Arumugam, T Kielian - Journal of Innate Immunity, 2023 - karger.com
Background: Staphylococcus aureus (S. aureus) is a common cause of hospital-and
community-acquired infections that can result in various clinical manifestations ranging from …

Reactive Oxygen‐Correlated Photothermal Imaging of Smart COF Nanoreactors for Monitoring Chemodynamic Sterilization and Promoting Wound Healing

X Zhu, T Feng, Y Chen, Y Xiao, W Wen, S Wang… - Small, 2024 - Wiley Online Library
Chemodynamic therapy (CDT) has emerged as a promising approach for treating infected
diabetic wounds, while reliable imaging technology for simultaneous monitoring of ROS and …

GSH-depleted Cu-covalent organic frameworks for multimodal synergistic therapy against diabetic infections

X Zhu, T Feng, Y Chen, Y Xiao, W Wen, X Zhang… - Chemical Engineering …, 2024 - Elsevier
Skin wound healing, particularly diabetic wound healing, is a common clinical challenge.
Reducing bacterial infection and promoting angiogenesis are key strategies for diabetic …

Advanced Fe-COF-based photothermal cascade nano-generator for sterilization and promoting wound healing

X Wu, T Feng, X Zhu, D Dong, Q Gao, S Huang… - Chemical Engineering …, 2024 - Elsevier
Pharmacological treatments of diabetic ulcers remain a huge challenge due to the impaired
angiogenesis and uncontrolled bacterial infection. Here, iminopyrazine-based Fe-covalent …

A Flexible Antibacterial Gel Electrochemiluminescence Device for Monitoring and Therapy of Chronic Diabetic Wounds

Y Yuan, D Yan, R Duan, H Xiong, W Wen, S Wang… - …, 2024 - Wiley Online Library
The rapid development of internal light‐driven photodynamic therapy stems from its
capability to eliminate bulky physical light sources, addressing the medical requirements for …

Role of sodium pyruvate in maintaining the survival and cytotoxicity of Staphylococcus aureus under high glucose conditions

T Chen, H Xu, X Yao, Z Luo - Frontiers in Microbiology, 2023 - frontiersin.org
Glucose is a crucial carbon source for the growth of Staphylococcus aureus, but an excess
of glucose is detrimental and even leads to cell death. Pyruvate, the central metabolite of …

[HTML][HTML] Syzygium zeylanicum (L.) DC. polyphenols exhibit anti-diabetic activity by modulation of ACC1, SGLT1, and GLP-1 genes and restoration of gut microbiota in …

MT Nguyen, VH Pham, MD Tran, QV Nguyen - Journal of Functional …, 2024 - Elsevier
Abstract Syzygium zeylanicum (L.) DC.(SZL) has long been used as a traditional remedy for
diabetes, but its underlying mechanisms of action remain unknown. This study aimed to …

[引用][C] Metabolism Shapes Immune Responses

PAT Kielian - 2023 - europepmc.org
Background: Staphylococcus aureus (S. aureus) is a common cause of hospital-and
community-acquired infections that can result in various clinical manifestations ranging from …