Genome-scale metabolic modeling of the human microbiome in the era of personalized medicine
The human microbiome plays an important role in human health and disease. Meta-omics
analyses provide indispensable data for linking changes in microbiome composition and …
analyses provide indispensable data for linking changes in microbiome composition and …
Dysregulation of metabolic flexibility: The impact of mTOR on autophagy in neurodegenerative disease
K Maiese - International review of neurobiology, 2020 - Elsevier
Non-communicable diseases (NCDs) that involve neurodegenerative disorders and
metabolic disease impact over 400 million individuals globally. Interestingly, metabolic …
metabolic disease impact over 400 million individuals globally. Interestingly, metabolic …
Mechanistic and data-driven models of cell signaling: Tools for fundamental discovery and rational design of therapy
A full understanding of cell signaling processes requires knowledge of protein structure–
function relationships, protein–protein interactions, and the abilities of pathways to control …
function relationships, protein–protein interactions, and the abilities of pathways to control …
TRIMER: Transcription regulation integrated with metabolic regulation
There has been extensive research in predictive modeling of genome-scale metabolic
reaction networks. Living systems involve complex stochastic processes arising from …
reaction networks. Living systems involve complex stochastic processes arising from …
Network Modeling and Control of Dynamic Disease Pathways, Review and Perspectives
Dynamic disease pathways are a combination of complex dynamical processes among bio-
molecules in a cell that leads to diseases. Network modeling of disease pathways considers …
molecules in a cell that leads to diseases. Network modeling of disease pathways considers …
Analysis of the potential and mechanism of Ginkgo biloba in the treatment of Alzheimer's disease based on network pharmacology
XY Huang, TT Li, L Zhou, T Liu, LL Xiong, CY Yu - Ibrain, 2021 - Wiley Online Library
Objective Study the principle and possible mechanism of Ginkgo biloba in the treatment of
Alzheimer's disease (AD) which is based on network pharmacology. Methods The potential …
Alzheimer's disease (AD) which is based on network pharmacology. Methods The potential …
[HTML][HTML] Disease global behavior: a systematic study of the human interactome network reveals conserved topological features among categories of diseases
Due to the complexity of human diseases, an inclusive approach such as network biology
may be an appropriate choice to study their mechanism and investigate similar or distinctive …
may be an appropriate choice to study their mechanism and investigate similar or distinctive …
International Review of Neurobiology
K Maiese - International Review of Neurobiology, 2020 - elibrary.ru
Non-communicable diseases (NCDs) that involve neurodegenerative disorders and
metabolic disease impact over 400 million individuals globally. Interestingly, metabolic …
metabolic disease impact over 400 million individuals globally. Interestingly, metabolic …
Predicting weighted unobserved nodes in a regulatory network using answer set programming
Background The impact of a perturbation, over-expression, or repression of a key node on
an organism, can be modelled based on a regulatory and/or metabolic network. Integration …
an organism, can be modelled based on a regulatory and/or metabolic network. Integration …
Sensitivity analysis of genome-scale metabolic flux prediction
TRIMER, Transcription Regulation Integrated with MEtabolic Regulation, is a genome-scale
modeling pipeline targeting at metabolic engineering applications. Using TRIMER …
modeling pipeline targeting at metabolic engineering applications. Using TRIMER …