[HTML][HTML] Lipids in atherosclerosis: pathophysiology and the role of calculated lipid indices in assessing cardiovascular risk in patients with hyperlipidemia

M Gaggini, F Gorini, C Vassalle - International journal of molecular …, 2022 - mdpi.com
The role of lipids is essential in any phase of the atherosclerotic process, which is
considered a chronic lipid-related and inflammatory condition. The traditional lipid profile …

Iron metabolism in cardiovascular disease: physiology, mechanisms, and therapeutic targets

KT Sawicki, A De Jesus, H Ardehali - Circulation research, 2023 - Am Heart Assoc
The cardiovascular system requires iron to maintain its high energy demands and metabolic
activity. Iron plays a critical role in oxygen transport and storage, mitochondrial function, and …

[HTML][HTML] Targeting a silent disease: vascular calcification in chronic kidney disease

C Marreiros, C Viegas, D Simes - International Journal of Molecular …, 2022 - mdpi.com
Chronic kidney disease (CKD) patients have a higher risk of developing early
cardiovascular disease (CVD). Although vascular calcification (VC) is one of the strongest …

[HTML][HTML] Iron in cardiovascular disease: challenges and potentials

S Li, X Zhang - Frontiers in cardiovascular medicine, 2021 - frontiersin.org
Iron is essential for many biological processes. Inadequate or excess amount of body iron
can result in various pathological consequences. The pathological roles of iron in …

[HTML][HTML] The Effects of Porphyromonas gingivalis on Atherosclerosis-Related Cells

J Zhang, M Xie, X Huang, G Chen, Y Yin, X Lu… - Frontiers in …, 2021 - frontiersin.org
Atherosclerosis (AS), one of the most common types of cardiovascular disease, has initially
been attributed to the accumulation of fats and fibrous materials. However, more and more …

Effects of fetuin-A with diverse functions and multiple mechanisms on human health

MA Icer, H Yıldıran - Clinical biochemistry, 2021 - Elsevier
Abstract Fetuin-A (Alfa 2-Heremans-Schmid) is a glycoprotein that is mainly synthesized by
hepatocytes and then released into the bloodstream. While fetuin-A, a multifunctional …

[HTML][HTML] Research models for studying vascular calcification

J Herrmann, M Babic, M Tölle, M van der Giet… - International journal of …, 2020 - mdpi.com
Calcification of the vessel wall contributes to high cardiovascular morbidity and mortality.
Vascular calcification (VC) is a systemic disease with multifaceted contributing and inhibiting …

[HTML][HTML] Ultrastructural pathology of atherosclerosis, calcific aortic valve disease, and bioprosthetic heart valve degeneration: commonalities and differences

A Kostyunin, R Mukhamadiyarov, T Glushkova… - International Journal of …, 2020 - mdpi.com
Atherosclerosis, calcific aortic valve disease (CAVD), and bioprosthetic heart valve
degeneration (alternatively termed structural valve deterioration, SVD) represent three …

[HTML][HTML] Vascular calcification: from the perspective of crosstalk

S Yang, Z Zeng, Q Yuan, Q Chen, Z Wang, H Xie… - Molecular …, 2023 - Springer
Vascular calcification (VC) is highly correlated with cardiovascular disease morbidity and
mortality, but anti-VC treatment remains an area to be tackled due to the ill-defined …

In silico analysis and verification of critical genes related to vascular calcification in multiple diseases

S Li, J Ruan, Z Yang, L Liu… - Cell Biochemistry and …, 2023 - Wiley Online Library
Identifying a functional molecular therapeutic target of vascular calcification (VC) that will not
affect normal osteogenic differentiation is a challenge. To address this aim, we screened the …