Biologically and therapeutically important hypoxia occurs in many solid tumor masses.
Hypoxia can be a direct cause of therapeutic resistance because some drugs and radiation …

This review discusses available clinical and experimental data and the underlying
mechanisms involved in trimodality treatment consisting of hyperthermia, cisplatin and …

PURPOSE To investigate the efficacy of combined hyperfractionated radiation therapy (HFX
RT) and concurrent chemotherapy (CHT) in stage IIIA or IIIB non-small-cell lung cancer …

The intention of this chapter is to review existing experimental data on combinations of
cytotoxic drugs and hyperthermia. The focus will be on those drugs which are the most likely …

Background Diffuse pontine gliomas remain one of the most lethal of pediatric malignancies
despite the use of increasingly intensive therapies. We delivered intensive chemotherapy …

Responses to the combination of cisplatin (CDDP) and radiation in experimental and clinical
studies have been reported to vary from high radiosensitization to clear sub‐additivity. We …

Retinoblastoma is a rare type of cancer of the eye, often developing in early childhood, that
affects the retina, the light sensitive tissue at the back of the eye that detects light and colour …

Purpose: To investigate the feasibility and activity of concurrent radiochemotherapy in
patients with Stage III nonsmall-cell lung cancer (NSCLC). Materials and Methods: Forty-one …

Purpose: We attempted in our clinic to evaluate the efficacy and feasibility of a simultaneous
application of a cis-platinum–based chemotherapy and interstitial hyperthermia to interstitial …

Although the combined modality approach to the clinical management of malignant disease
is now accepted practice for the majority of cancers, the requirement to define optimal …