The complex link between NAFLD and type 2 diabetes mellitus—mechanisms and treatments
Nonalcoholic fatty liver disease (NAFLD) has reached epidemic proportions worldwide.
NAFLD and type 2 diabetes mellitus (T2DM) are known to frequently coexist and act …
NAFLD and type 2 diabetes mellitus (T2DM) are known to frequently coexist and act …
Omega‐3 fatty acids for the primary and secondary prevention of cardiovascular disease
AS Abdelhamid, TJ Brown, JS Brainard… - Cochrane Database …, 2018 - cochranelibrary.com
Background Researchers have suggested that omega‐3 polyunsaturated fatty acids from
oily fish (long‐chain omega‐3 (LCn3), including eicosapentaenoic acid (EPA) and …
oily fish (long‐chain omega‐3 (LCn3), including eicosapentaenoic acid (EPA) and …
Update on NAFLD genetics: from new variants to the clinic
Non-alcoholic fatty liver disease (NAFLD) is the leading cause of liver diseases in high-
income countries and the burden of NAFLD is increasing at an alarming rate. The risk of …
income countries and the burden of NAFLD is increasing at an alarming rate. The risk of …
Effects of dapagliflozin and n-3 carboxylic acids on non-alcoholic fatty liver disease in people with type 2 diabetes: a double-blind randomised placebo-controlled …
JW Eriksson, P Lundkvist, PA Jansson, L Johansson… - Diabetologia, 2018 - Springer
Abstract Aims/hypothesis The EFFECT-II study aimed to investigate the effects of
dapagliflozin and omega-3 (n-3) carboxylic acids (OM-3CA), individually or combined, on …
dapagliflozin and omega-3 (n-3) carboxylic acids (OM-3CA), individually or combined, on …
[HTML][HTML] KASL clinical practice guidelines: management of nonalcoholic fatty liver disease
The prevalence of nonalcoholic fatty liver disease (NAFLD) is increasing rapidly worldwide
as the obese and diabetic populations increase, and it has been estimated to be 20–30% in …
as the obese and diabetic populations increase, and it has been estimated to be 20–30% in …
Retracted: M2 Macrophage–Derived Exosomes Facilitate HCC Metastasis by Transferring αMβ2 Integrin to Tumor Cells
J Wu, W Gao, Q Tang, Y Yu, W You, Z Wu, Y Fan… - …, 2021 - Wiley Online Library
Background and Aims The development and progression of hepatocellular carcinoma
(HCC) is dependent on its local microenvironment. Tumor‐associated macrophages (TAMs) …
(HCC) is dependent on its local microenvironment. Tumor‐associated macrophages (TAMs) …
Bioactive lipid species and metabolic pathways in progression and resolution of nonalcoholic steatohepatitis
G Musso, M Cassader, E Paschetta, R Gambino - Gastroenterology, 2018 - Elsevier
The prevalence of nonalcoholic steatohepatitis (NASH) is increasing worldwide, yet there
are no effective treatments. A decade has passed since the initial lipidomics analyses of liver …
are no effective treatments. A decade has passed since the initial lipidomics analyses of liver …
Non-alcoholic fatty liver disease: an emerging driving force in chronic kidney disease
G Targher, CD Byrne - Nature Reviews Nephrology, 2017 - nature.com
Non-alcoholic fatty liver disease (NAFLD) is caused by an accumulation of fat in the liver; the
condition can progress over time to increase the risk of developing cirrhosis, end-stage liver …
condition can progress over time to increase the risk of developing cirrhosis, end-stage liver …
[HTML][HTML] Polyunsaturated fatty acids for the primary and secondary prevention of cardiovascular disease
AS Abdelhamid, N Martin, C Bridges… - … of systematic reviews, 2018 - ncbi.nlm.nih.gov
Background Evidence on the health effects of total polyunsaturated fatty acids (PUFA) is
equivocal. Fish oils are rich in omega‐3 PUFA and plant oils in omega‐6 PUFA. Evidence …
equivocal. Fish oils are rich in omega‐3 PUFA and plant oils in omega‐6 PUFA. Evidence …
Leveraging human genetics to identify potential new treatments for fatty liver disease
Fatty liver disease (FLD), including its more severe pathologies, namely steatohepatitis,
hepatocarcinoma, and cirrhosis, is the most common cause of chronic liver disease …
hepatocarcinoma, and cirrhosis, is the most common cause of chronic liver disease …