Recent advances in defining the molecular signaling pathways that regulate the
phagocytosis of apoptotic cells have improved our understanding of this complex and …

Cancer immunotherapy utilizing T‐cell checkpoint inhibitors has shown tremendous clinical
success. Yet, this mode of treatment is effective in only a subset of patients. Unresponsive …

The induction of tumor cell death is one of the major goals of radiotherapy and has been
considered to be the central determinant of its therapeutic outcome for a long time. However …

The ultimate and most favorable fate of almost all dying cells is engulfment by neighboring
or specialized cells. Efficient clearance of cells undergoing apoptotic death is crucial for …

In antiphospholipid syndrome (APS), antiphospholipid antibodies (aPL) binding to β2
glycoprotein I (β2GPI) induce endothelial cell–leukocyte adhesion and thrombus formation …

Cells are able to execute apoptosis by activating series of specific biochemical reactions.
One of the most prominent characteristics of cell death is the externalization of …

Several cationic antimicrobial peptides (AMPs) have recently been shown to display
anticancer activity via a mechanism that usually entails the disruption of cancer cell …

Chemotherapy has historically been thought to induce cancer cell death in an
immunogenically silent manner. However, recent studies have demonstrated that …

There is a pressing need for antiviral agents that are effective against multiple classes of
viruses. Broad specificity might be achieved by targeting phospholipids that are widely …

Multiple tumor-derived factors are responsible for the accumulation and expansion of
immune-suppressing myeloid-derived suppressor cells (MDSC) and M2-like tumor …