Microglia activation is observed in various neurodegenerative diseases. Recent advances in
single-cell technologies have revealed that these reactive microglia were with high spatial …

Anecdotal evidence that cannabis preparations have medical benefits together with the
discovery of the psychotropic plant cannabinoid Δ9-tetrahydrocannabinol (THC) initiated …

Apart from having been used and misused for at least four millennia for, among others,
recreational and medicinal purposes, the cannabis plant and its most peculiar chemical …

Background: Numerous physical, psychological, and emotional benefits have been
attributed to marijuana since its first reported use in 2,600 BC in a Chinese pharmacopoeia …

The endocannabinoid system (ECS) is composed of two G protein-coupled receptors
(GPCRs), the cannabinoid CB1 and CB2 receptors, and the two main endogenous lipid …

Astrocytes contribute to the maintenance of the health and function of the central nervous
system (CNS). Thus, it is not surprising that these multifunctional cells have been implicated …

Huntington's disease (HD) is an autosomal dominant neurodegenerative disease. HD
patients present with movement disorders, behavioral and psychiatric symptoms and …

Microglia are key to maintaining the homeostasis of the brain. These immune cells of the
brain can be our biggest ally in fighting infections, but can worsen pathology or hinder …

The identification of the human cannabinoid receptors and their roles in health and disease,
has been one of the most significant biochemical and pharmacological advancements to …

The discovery of the endocannabinoid system, comprising the G‐protein coupled
cannabinoid 1 and 2 receptors (CB 1/2), their endogenous lipid ligands or …