Toxicity of mercury: Molecular evidence

L Yang, Y Zhang, F Wang, Z Luo, S Guo, U Strähle - Chemosphere, 2020 - Elsevier
Minamata disease in Japan and the large-scale poisoning by methylmercury (MeHg) in Iraq
caused wide public concerns about the risk emanating from mercury for human health …

In situ imaging of metals in cells and tissues

R McRae, P Bagchi, S Sumalekshmy… - Chemical …, 2009 - ACS Publications
Approximately one third of the human proteome contains metal cations, either in the form of
cofactors with catalytic functions or as structural support elements. 1, 2 To guarantee a …

Apoptotic effect of eugenol in human colon cancer cell lines

SK Jaganathan, A Mazumdar, D Mondhe… - Cell biology …, 2011 - Wiley Online Library
Eugenol, a natural compound available in honey and various plants extracts including
cloves and Magnoliae flos, is exploited for various medicinal applications. Since most of the …

Effect of vitamin B6 on oxygen radicals, mitochondrial membrane potential, and lipid peroxidation in H2O2-treated U937 monocytes

K Kannan, SK Jain - Free Radical Biology and Medicine, 2004 - Elsevier
Vitamin B6 (Vit. B6) supplementation has been shown to be beneficial in reducing diabetic
complications, cognitive aging, and in the prevention of coronary heart disease. It was …

Plasma membrane aquaporin activity can affect the rate of apoptosis but is inhibited after apoptotic volume decrease

EM Jablonski, AN Webb… - … of Physiology-Cell …, 2004 - journals.physiology.org
Apoptosis is characterized by a conserved series of morphological events beginning with
the apoptotic volume decrease (AVD). This study investigated a role for aquaporins (AQPs) …

Low-level methylmercury exposure causes human T-cells to undergo apoptosis: evidence of mitochondrial dysfunction

BJ Shenker, TL Guo, IM Shapiro - Environmental Research, 1998 - Elsevier
There is growing evidence that heavy metals, in general, and mercurial compounds, in
particular, are immunotoxic to the human immune system. The major focus of our study is to …

Evidence for the induction of apoptosis by endosulfan in a human T-cell leukemic line

K Kannan, RF Holcombe, SK Jain… - Molecular and Cellular …, 2000 - Springer
Several organochlorinated pesticides including DDT, PCBs and dieldrin have been reported
to cause immune suppression and increase susceptibility to infection in animals. Often this …

Involvement of non-protein thiols, mitochondrial dysfunction, reactive oxygen species and p53 in honey-induced apoptosis

SK Jaganathan, M Mandal - Investigational new drugs, 2010 - Springer
Honey is a complex mixture of different biologically active constituents. Honey possesses
anti-inflammatory, antioxidant and antitumor properties. Our chief investigation was to …

Induction of apoptosis in human T cells by Actinobacillus actinomycetemcomitans cytolethal distending toxin is a consequence of G2 arrest of the cell cycle

BJ Shenker, RH Hoffmaster, A Zekavat… - The Journal of …, 2001 - journals.aai.org
We have previously shown that Actinobacillus actinomycetemcomitans produces an
immunosuppressive factor that is encoded by the cdtB gene, which is homologous to a …

[HTML][HTML] Mercuric compounds inhibit human monocyte function by inducing apoptosis: evidence for formation of reactive oxygen species, development of …

O InSug, S Datar, CJ Koch, IM Shapiro, BJ Shenker - Toxicology, 1997 - Elsevier
The focus of this investigation was to examine the effects of low concentrations of organic
mercuric compounds on human monocyte function and to relate these effects to apoptosis …