Despite continuous progress in medicine, sepsis remains the main cause of deaths in the
intensive care unit. Liver failure complicating sepsis/septic shock has a significant impact on …

For a number of chronic diseases, including cirrhosis, it has been a challenging issue for
physicians to elaborate reliable tools for predicting outcome. The principal goal is to …

During sepsis, the liver plays a key role. It is implicated in the host response, participating in
the clearance of the infectious agents/products. Sepsis also induces liver damage through …

Once patients with cirrhosis experience decompensation, early mortality risk increases
sharply. Liver transplantation has transformed the prognosis of decompensated cirrhosis …

Intestinal failure (IF) is the critical reduction of the gut mass or its function below the minimum
needed to absorb nutrients and fluids required for adequate growth in children. Severe IF …

Jaundice is a well-known complication of sepsis or extrabacterial infection. Sepsis and
bacterial infection are responsible for up to 20% of cases of jaundice in patients of all ages …

Hepatobiliary transport systems are essential for the uptake and excretion of a variety of
compounds including bile acids. Disruption and dysregulation of this excretory pathway …

Objective: In critically ill patients, hepatic dysfunction is regarded as a late organ failure
associated with poor prognosis. We investigated the incidence and prognostic implications …

Cholestasis is a common complication in patients with extrahepatic bacterial infection and
sepsis. This article gives a comprehensive overview of the molecular and cellular …

Introduction Regional citrate anticoagulation (RCA) for continuous renal replacement
therapy is widely used in intensive care units (ICUs). However, concern exists about the …