The crosstalk between Nrf2 and NF-κB pathways in coronary artery disease: Can it be regulated by SIRT6?

E Casper - Life sciences, 2023 - Elsevier
Coronary artery disease (CAD) is the leading cause of death worldwide. Oxidative stress
and inflammation are major mechanisms responsible for the progression of CAD. Nuclear …

Natural allies for heart health: Nrf2 Activation and cardiovascular disease management

SU Khan, SU Khan, M Suleman, MU Khan… - Current Problems in …, 2024 - Elsevier
The term “cardiovascular diseases”(CVD) refers to various ailments that affect the heart and
blood vessels, including myocardial ischemia, congenital heart defects, heart failure …

Sex-Based Outcomes of Dual-Antiplatelet Therapy After Percutaneous Coronary Intervention: A Pairwise and Network Meta-Analysis

TA Agbaedeng, JJ Noubiap, KA Roberts, DP Chew… - Drugs, 2024 - Springer
Background Although dual antiplatelet therapy (DAPT) improves the outcomes of patients
undergoing percutaneous coronary intervention (PCI), sex-specific differences in efficacy …

Sex differences at the platelet–vascular interface

A Sabetta, L Lombardi, L Stefanini - Internal and Emergency Medicine, 2022 - Springer
Platelets are multifunctional cells that ensure the integrity of the vascular wall and modulate
the immune response at the blood/vascular interface. Their pathological activation results in …

Adherence to the Mediterranean Diet in Preventing Major Cardiovascular Events in Patients with Ischemic Heart Disease: The EVA Study

R Cangemi, M Miglionico, T D'Amico, S Fasano… - Nutrients, 2023 - mdpi.com
Background: Adherence to healthy dietary patterns, such as the Mediterranean diet (Med-
diet), is recommended for the maintenance of cardiovascular health. The determinants for …

Sex and Gender in Ageing and Longevity: Highlights from an International Course

G Candore, G Accardi, A Aiello… - Translational …, 2024 - pmc.ncbi.nlm.nih.gov
Gender medicine is a multidisciplinary science and represents an important perspective for
pathophysiological and clinical studies in the third millennium. Here, it is provided an …

Putative causal inference for the relationship between obesity and sex hormones in males: a bidirectional Mendelian randomization study

B Wan, N Ma, Z Zhou, C Lv - PeerJ, 2023 - peerj.com
Background Obesity is a chronic disease with a high prevalence rate and is an established
risk factor for human health. Body mass index (BMI) is a common and primary indicator used …

Network segregation in aging females and evaluation of the impact of sex steroid hormones

TH Hicks, TNC Magalhães, HK Ballard… - Frontiers in human …, 2023 - frontiersin.org
Males and females show differential patterns in connectivity in resting-state networks (RSNs)
during normal aging, from early adulthood to late middle age. Age-related differences in …

Demographic diversity in platelet function and response to antiplatelet therapy

K Jain, T Tyagi, SX Gu, EVS Faustino, J Hwa - Trends in Pharmacological …, 2024 - cell.com
Recent studies have highlighted the complexity of platelet biology, revealing their diverse
roles beyond hemostasis. Pathological platelet activation is now recognized as a key …

Melatonin ameliorates inflammation and improves outcomes of ischemia/reperfusion injury in patients undergoing coronary artery bypass grafting surgery: a …

EA Casper, LE Wakeel, NA Sabri, R Khorshid… - Apoptosis, 2024 - Springer
To investigate the protective role of high dose melatonin concerning myocardial I/R injury
and inflammation in patients undergoing on-pump coronary artery bypass grafting (CABG) …