Simple Summary Hepatocellular carcinoma (HCC) is the most frequent primitive cancer of
the liver, accounting for 90% of all recorded cases. HCC is the third most common cause of …

Simple Summary Patients with unresectable hepatocellular carcinoma (HCC), the most
common primary tumor of the liver, have poor prognosis and are increasing worldwide. The …

The incidence and mortality of hepatocellular carcinoma (HCC) are on a rise in the Western
countries including US, attributed mostly to late detection. Sorafenib has been the first-line …

Simple Summary Hepatitis B virus (HBV) is the main cause of hepatocellular carcinoma
(HCC) morbidity and mortality. Because of chemoresistance, sorafenib, the first-line systemic …

Background. Hepatocellular carcinoma (HCC) is the most common subtype of primary liver
cancer, which was highly correlated with metabolic dysfunction. Nevertheless, the …

Significance: KRIT1 (Krev interaction trapped 1) is a scaffolding protein that plays a critical
role in vascular morphogenesis and homeostasis. Its loss-of-function has been …

Oxidative stress (OS) is a condition in which the body has an unbalanced oxidative and
antioxidant effect. Oxidative stress has emerged as a critical component in the onset and …

Multimodal treatment is an important tool to overcome tumor drug resistance. The reactive
oxygen species (ROS) generated by photodynamic therapy (PDT) can directly play a killing …

Background Epidemiological studies investigating the potential associations between
antioxidant vitamins intake and risk of glioma have yielded inconsistent results. To address …

Simple Summary In the past decade, tyrosine kinase inhibitors sorafenib and regorafenib
have been standard treatments for advanced liver cancer. Previous studies have associated …