[HTML][HTML] A role for microfluidic systems in precision medicine
JM Ayuso, M Virumbrales-Muñoz, JM Lang… - Nature …, 2022 - nature.com
Precision oncology continues to challenge the “one-size-fits-all” dogma. Under the precision
oncology banner, cancer patients are screened for molecular tumor alterations that predict …
oncology banner, cancer patients are screened for molecular tumor alterations that predict …
[HTML][HTML] A review of circulating tumour cell enrichment technologies
AJ Rushton, G Nteliopoulos, JA Shaw, RC Coombes - Cancers, 2021 - mdpi.com
Simple Summary Circulating tumour cells (CTCs) are cancer cells shed into the bloodstream
from tumours and their analysis can provide important insights into cancer detection and …
from tumours and their analysis can provide important insights into cancer detection and …
A conduit to metastasis: circulating tumor cell biology
DS Micalizzi, S Maheswaran… - Genes & …, 2017 - genesdev.cshlp.org
Advances in the enrichment and analysis of rare cells from the bloodstream have allowed for
detection and characterization of circulating tumor cells (CTCs) from patients with cancer …
detection and characterization of circulating tumor cells (CTCs) from patients with cancer …
Fundamentals and applications of inertial microfluidics: A review
In the last decade, inertial microfluidics has attracted significant attention and a wide variety
of channel designs that focus, concentrate and separate particles and fluids have been …
of channel designs that focus, concentrate and separate particles and fluids have been …
[HTML][HTML] Circulating tumor cell technologies
MM Ferreira, VC Ramani, SS Jeffrey - Molecular oncology, 2016 - Elsevier
Circulating tumor cells, a component of the “liquid biopsy”, hold great potential to transform
the current landscape of cancer therapy. A key challenge to unlocking the clinical utility of …
the current landscape of cancer therapy. A key challenge to unlocking the clinical utility of …
Cancer diagnosis: from tumor to liquid biopsy and beyond
Technological advancements in research on circulating biomarkers from patient derived
blood have enabled a less invasive means of diagnosing non-hematologic cancers …
blood have enabled a less invasive means of diagnosing non-hematologic cancers …
Ultra-fast, label-free isolation of circulating tumor cells from blood using spiral microfluidics
Circulating tumor cells (CTCs) are rare cancer cells that are shed from primary or metastatic
tumors into the peripheral blood circulation. Phenotypic and genetic characterization of …
tumors into the peripheral blood circulation. Phenotypic and genetic characterization of …
Challenges in circulating tumour cell research
C Alix-Panabières, K Pantel - Nature Reviews Cancer, 2014 - nature.com
During the past ten years, circulating tumour cells (CTCs) have received enormous attention
as new biomarkers and the subject of basic research. Although CTCs are already used in …
as new biomarkers and the subject of basic research. Although CTCs are already used in …
A review of sorting, separation and isolation of cells and microbeads for biomedical applications: microfluidic approaches
Several biomedical analyses are performed on particular types of cells present in body
samples or using functionalized microparticles. Success in such analyses depends on the …
samples or using functionalized microparticles. Success in such analyses depends on the …
[HTML][HTML] High throughput, label-free isolation of circulating tumor cell clusters in meshed microwells
M Boya, T Ozkaya-Ahmadov, BE Swain, CH Chu… - Nature …, 2022 - nature.com
Extremely rare circulating tumor cell (CTC) clusters are both increasingly appreciated as
highly metastatic precursors and virtually unexplored. Technologies are primarily designed …
highly metastatic precursors and virtually unexplored. Technologies are primarily designed …