Challenges of anticoagulant therapy in atrial fibrillation—focus on gastrointestinal bleeding
A Scridon, AI Balan - International Journal of Molecular Sciences, 2023 - mdpi.com
The rising prevalence and the complexity of atrial fibrillation (AF) pose major clinical
challenges. Stroke prevention is accompanied by non-negligible risks, making anticoagulant …
challenges. Stroke prevention is accompanied by non-negligible risks, making anticoagulant …
Systematic review and meta-analysis of direct oral anticoagulants versus warfarin in atrial fibrillation with low stroke risk
Pivotal trials comparing direct oral anticoagulants (DOACs) against warfarin in patients with
atrial fibrillation (AF) predominantly involved patients with high stroke risk. This study aimed …
atrial fibrillation (AF) predominantly involved patients with high stroke risk. This study aimed …
Eight pharmacokinetic genetic variants are not associated with the risk of bleeding from direct oral anticoagulants in non-valvular atrial fibrillation patients
Background: Atrial fibrillation (AF) is the leading cause of ischemic stroke and treatment has
focused on reducing this risk through anticoagulation. Direct Oral Anticoagulants (DOACs) …
focused on reducing this risk through anticoagulation. Direct Oral Anticoagulants (DOACs) …
Direct oral anticoagulants as the first choice of anticoagulation for patients with peripheral artery disease to prevent adverse vascular events: a systematic review and …
The best method of anticoagulation for patients with peripheral artery disease (PAD) is still a
topic of interest for physicians. We conducted a meta-analysis to compare the effects of …
topic of interest for physicians. We conducted a meta-analysis to compare the effects of …
Pharmacotherapy for stroke prevention in nonvalvular atrial fibrillation: current strategies and future directions
A Gómez-Outes, ML Suárez-Gea… - Expert Opinion on …, 2022 - Taylor & Francis
Introduction Cardioembolic stroke, associated to nonvalvular atrial fibrillation (NVAF),
accounts for approximately one in every four strokes. Cardioembolic stroke has a bad …
accounts for approximately one in every four strokes. Cardioembolic stroke has a bad …
Direct comparison of non-vitamin K antagonist oral anticoagulant versus warfarin for stroke prevention in non-valvular atrial fibrillation: a systematic review and meta …
Background To overcome the several drawbacks of warfarin, non-vitamin K antagonist oral
anticoagulants (NOACs) were developed. Even though randomized controlled trials (RCTs) …
anticoagulants (NOACs) were developed. Even though randomized controlled trials (RCTs) …
Non‐synonymous alterations in AKR7A3 and ABCA6 correlate with bleeding in aged patients treated with rivaroxaban
Rivaroxaban is an oral anticoagulant that inhibits thrombin and blocks coagulation cascade
through directly inactivating factors Xa. Despite rivaroxaban is widely used for prevention …
through directly inactivating factors Xa. Despite rivaroxaban is widely used for prevention …
Challenges to Laboratory Monitoring of Direct Oral Anticoagulants
J Qiao, MH Tran - Clinical and Applied Thrombosis …, 2024 - journals.sagepub.com
Direct oral anticoagulants (DOACs) exert anticoagulation effect by directly inhibiting Factor
Xa (rivaroxaban, apixaban, and edoxaban) or thrombin (dabigatran). Though DOACs are …
Xa (rivaroxaban, apixaban, and edoxaban) or thrombin (dabigatran). Though DOACs are …
Risk of intracranial hemorrhage between different direct oral anticoagulants in older patients seen in the emergency department with a head injury: A population …
Introduction Patients taking direct oral anticoagulants (DOACs) are increasingly managed in
emergency departments (ED). It is unknown whether the risk of traumatic intracranial …
emergency departments (ED). It is unknown whether the risk of traumatic intracranial …
Mobile cardiac outpatient telemetry patch vs implantable loop recorder in cryptogenic stroke patients in the US–cost-minimization model
G Medic, N Kotsopoulos, MP Connolly… - Medical Devices …, 2021 - Taylor & Francis
Purpose The aim of this study was to compare costs and outcomes of mobile cardiac
outpatient telemetry (MCOT) patch followed by implantable loop recorder (ILR) compared to …
outpatient telemetry (MCOT) patch followed by implantable loop recorder (ILR) compared to …