Airway remodeling heterogeneity in asthma and its relationship to disease outcomes
A Hsieh, N Assadinia, TL Hackett - Frontiers in physiology, 2023 - frontiersin.org
Asthma affects an estimated 262 million people worldwide and caused over 461,000 deaths
in 2019. The disease is characterized by chronic airway inflammation, reversible …
in 2019. The disease is characterized by chronic airway inflammation, reversible …
Airway remodelling in asthma: from benchside to clinical practice
C Bergeron, MK Tulic, Q Hamid - Canadian respiratory journal, 2010 - Wiley Online Library
Airway remodelling refers to the structural changes that occur in both large and small
airways relevant to miscellaneous diseases including asthma. In asthma, airway structural …
airways relevant to miscellaneous diseases including asthma. In asthma, airway structural …
Remodeling in asthma
C Bergeron, W Al-Ramli, Q Hamid - Proceedings of the American …, 2009 - atsjournals.org
Airway remodeling refers to the structural changes that occur in both the large and the small
airways of miscellaneous diseases, including asthma. In asthma, airway structural changes …
airways of miscellaneous diseases, including asthma. In asthma, airway structural changes …
Structural changes in airway diseases: characteristics, mechanisms, consequences, and pharmacologic modulation
C Bergeron, LP Boulet - Chest, 2006 - Elsevier
In airway diseases such as asthma and COPD, specific structural changes may be
observed, very likely secondary to an underlying inflammatory process. Although it is still …
observed, very likely secondary to an underlying inflammatory process. Although it is still …
[HTML][HTML] Mechanics of pulmonary airways: linking structure to function through constitutive modeling, biochemistry, and histology
Breathing involves fluid-solid interactions in the lung; however, the lack of experimental data
inhibits combining the mechanics of air flow to airway deformation, challenging the …
inhibits combining the mechanics of air flow to airway deformation, challenging the …
Tidal stretches do not modulate responsiveness of intact airways in vitro
Studies on isolated tracheal airway smooth muscle (ASM) strips have shown that
length/force fluctuations, similar to those likely occurring during breathing, will mitigate ASM …
length/force fluctuations, similar to those likely occurring during breathing, will mitigate ASM …
It's not all smooth muscle: non-smooth-muscle elements in control of resistance to airflow
To achieve gas exchange, inspired air must pass through an intricate and dynamic
tracheobronchial tree. The tree offers resistance to airflow, and increased resistance is the …
tracheobronchial tree. The tree offers resistance to airflow, and increased resistance is the …
Airway narrowing and bronchodilation to deep inspiration in bronchial segments from subjects with and without reported asthma
PB Noble, RL Jones, A Cairncross… - Journal of applied …, 2013 - journals.physiology.org
The present study presents preliminary findings on how structural/functional abnormalities of
the airway wall relate to excessive airway narrowing and reduced bronchodilatory response …
the airway wall relate to excessive airway narrowing and reduced bronchodilatory response …
Airway wall remodeling in asthma: from the epithelial layer to the adventitia
Asthma is an episodic respiratory syndrome caused by several pathogenic processes. This
recurrent syndrome is associated with an accelerated decline in lung function and increase …
recurrent syndrome is associated with an accelerated decline in lung function and increase …
Models to study airway smooth muscle contraction in vivo, ex vivo and in vitro: implications in understanding asthma
Asthma is a chronic obstructive airway disease characterised by airway
hyperresponsiveness (AHR) and airway wall remodelling. The effector of airway narrowing …
hyperresponsiveness (AHR) and airway wall remodelling. The effector of airway narrowing …