[HTML][HTML] In vitro lung models and their application to study SARS-CoV-2 pathogenesis and disease
N Heinen, M Kloehn, E Steinmann, S Pfaender - Viruses, 2021 - mdpi.com
SARS-CoV-2 has spread across the globe with an astonishing velocity and lethality that has
put scientist and pharmaceutical companies worldwide on the spot to develop novel …
put scientist and pharmaceutical companies worldwide on the spot to develop novel …
[HTML][HTML] 3D lung tissue models for studies on SARS-CoV-2 pathophysiology and therapeutics
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), causing the coronavirus
disease 2019 (COVID-19), has provoked more than six million deaths worldwide and …
disease 2019 (COVID-19), has provoked more than six million deaths worldwide and …
[HTML][HTML] COVID-19-associated myocarditis: an evolving concern in cardiology and beyond
M Fraser, ACC Agdamag, VR Maharaj, M Mutschler… - Biology, 2022 - mdpi.com
Simple Summary Coronavirus disease-2019 (COVID-19) affects many organs in the body,
including the heart. One complication of particular concern is inflammation of the heart …
including the heart. One complication of particular concern is inflammation of the heart …
[HTML][HTML] Lung-centric inflammation of COVID-19: potential modulation by vitamin D
HMA Fakhoury, PR Kvietys, I Shakir, H Shams… - Nutrients, 2021 - mdpi.com
SARS-CoV-2 infects the respiratory tract and leads to the disease entity, COVID-19.
Accordingly, the lungs bear the greatest pathologic burden with the major cause of death …
Accordingly, the lungs bear the greatest pathologic burden with the major cause of death …
[HTML][HTML] Experimental models to study COVID-19 effect in stem cells
RM Chugh, P Bhanja, A Norris, S Saha - Cells, 2021 - mdpi.com
The new strain of coronavirus (severe acute respiratory syndrome coronavirus type 2 (SARS-
CoV-2)) emerged in 2019 and hence is often referred to as coronavirus disease 2019 …
CoV-2)) emerged in 2019 and hence is often referred to as coronavirus disease 2019 …
Modeling infectious diseases of the central nervous system with human brain organoids
Bacteria, fungi, viruses, and protozoa are known to infect and induce diseases in the human
central nervous system (CNS). Modeling the mechanisms of interaction between pathogens …
central nervous system (CNS). Modeling the mechanisms of interaction between pathogens …
Inflammatory pathways and potential therapies for COVID-19: A mini review
AM Dabbish, N Yonis, M Salama… - European Journal …, 2021 - journals.sagepub.com
The public health crisis of the novel coronavirus disease (COVID-19) is alarming since
January 2020. COVID-19 genome (SARS-CoV-2) is related to other highly pathogenic …
January 2020. COVID-19 genome (SARS-CoV-2) is related to other highly pathogenic …
[HTML][HTML] Magnitude and timing of the antiviral response determine SARS-CoV-2 replication early in infection
NR Cheemarla, TA Watkins, VT Mihaylova, B Wang… - medrxiv, 2021 - ncbi.nlm.nih.gov
The interferon response is a potent antiviral defense mechanism, but its effectiveness
depends on its timing relative to viral replication. Here, we report viral replication and host …
depends on its timing relative to viral replication. Here, we report viral replication and host …