BACKGROUND Although laboratory procedures, along with culture media formulations,
have improved over the past two decades, the issue remains that human IVF is performed in …

The oocyte is the major determinant of embryo developmental competence in women. It
delivers half the chromosomal complement to the embryo, but the maternal and paternal …

The phenotype of the human embryo conceived through in vitro fertilization (IVF), that is its
morphology, developmental kinetics, physiology and metabolism, can be affected by …

BACKGROUND: The clinical efficacy of the current methods used for cryopreservation of
metaphase II human oocytes is low. Meiotic spindle disorders are thought to be largely …

With increased use of comprehensive chromosome screening (CCS), the question remains
as to why some practices do not experience the same high levels of clinical success after …

Assisted reproductive technology (ART) has led to the birth of millions of babies. In cattle,
thousands of embryos are produced annually. However, since the introduction and …

This study assesses meiotic spindle and zona pellucida characteristics using the PolScope,
and analyses their relationship to embryonic development potential. A total of 205 matured …

Incubators in the IVF laboratory play a pivotal role in providing a stable and appropriate
culture environment required for optimizing embryo development and clinical outcomes …

Meiotic spindles tether the chromosomes of oocytes and have been found to be structurally
abnormal in older women. Conventional methods to image the meiotic spindle, such as …

BACKGROUND: To examine the relationship between the meiotic spindle, the first cleavage
plane and any resulting influence on embryonic development parameters. METHODS …