Next-generation sequencing (NGS) technology has expanded in the last decades with
significant improvements in the reliability, sequencing chemistry, pipeline analyses, data …

Abstract The flavonoids, baicalin (5, 6-dihydroxy-2-phenyl-4H-1-benzopyran-4-one-7-Od-β-
glucuronic acid) 1 and its aglycone, baicalein 2 are found in edible medicinal plants …

Genome-wide association studies (GWAS) provide an agnostic approach for investigating
the genetic basis of complex diseases. In oncology, GWAS of nearly all common …

Sporadic colorectal cancer (CRC) is a somatic genetic disease in which pathogenesis is
influenced by the local colonic environment and the patient's genetic background …

Most genetic susceptibility to cutaneous melanoma remains to be discovered. Meta-analysis
genome-wide association study (GWAS) of 36,760 cases of melanoma (67% newly …

Chromatin profiling has emerged as a powerful means of genome annotation and detection
of regulatory activity. The approach is especially well suited to the characterization of non …

Background & Aims Guidelines for initiating colorectal cancer (CRC) screening are based
on family history but do not consider lifestyle, environmental, or genetic risk factors. We …

This review gives an account of recent advances in our knowledge of the molecular
mechanisms in colorectal cancer. Genetic changes in the germ line, combined with somatic …

Abstract BACKGROUND. The American Cancer Society, the Centers for Disease Control
and Prevention (CDC), the National Cancer Institute (NCI), and the North American …

In the past few years genome-wide association (GWA) studies have uncovered a large
number of convincingly replicated associations for many complex human diseases …