Gene therapies are currently one of the most investigated therapeutic modalities in both the
preclinical and clinical settings and have shown promise in treating a diverse spectrum of …

The human genetic code encrypted in thousands of genes holds the secret for synthesis of
proteins that drive all biological processes necessary for normal life and death. Though the …

Transposable elements are known by many names, including 'transposons','interspersed
repeats','selfish genetic elements','jumping genes', and 'parasitic DNA', but here we will refer …

Summary Antisense Piwi-interacting RNAs (piRNAs) guide silencing of established
transposons during germline development, and sense piRNAs drive ping-pong amplification …

The discovery of exoplanets within putative habitable zones revolutionized astrobiology in
recent years. It stimulated interest in the question about the origin of life and its evolution …

Transposable elements are the largest individual constituent of mammalian genomes.
These elements are highly diverse, a consequence of the multiplicity of genomic habitats …

Horizontal gene transfer from viruses to eukaryotic cells is a pervasive phenomenon.
Somatic viral integrations are linked to persistent viral infection whereas integrations into …

Despite only comprising half of all known viral species, RNA viruses are disproportionately
responsible for many of the worst epidemics in human history, including outbreaks of …

Transposons were once thought to be junk repetitive DNA in the genome. However, their
importance gradually became apparent as it became clear that they regulate gene …

The deep history and early diversification of retroviruses remains elusive, largely because
few retroviruses have been characterized in vertebrates other than mammals and birds …